Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.46 |
| ▸ | GABRD | O14764 | 2/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.46 |
| ▸ | GABRE | P78334 | 2/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL1134610 | 1.00 | TDP1 (0.59) | TDP1LMNAEGLN1ALKBH5SUCNR1 | |
| Succinic Acid SCHEMBL28420959 | 0.95 | TDP1 (0.53) | TDP1LMNAEGLN1ALKBH5SUCNR1 | |
| Adipic Acid SCHEMBL28436413 | 0.92 | LMNA (0.55) | TDP1LMNAOR51E2ALDH1A1SLC22A6 | |
| Succinic Acid SCHEMBL15366423 | 0.92 | TDP1 (0.50) | TDP1LMNAEGLN1ALKBH5SUCNR1 | |
| Sebacic Acid SCHEMBL29223184 | 0.90 | TSHR (0.57) | TDP1LMNAOR51E2ALDH1A1SLC22A6 | |
| Levulinic Acid SCHEMBL28012251 | 0.90 | LMNA (0.67) | TDP1LMNAEGLN1ALKBH5SUCNR1 | |
| Adipic Acid SCHEMBL10936251 | 0.89 | LMNA (0.58) | TDP1LMNAOR51E2ALDH1A1SLC22A6 | |
| Propylene Glycol SCHEMBL11367010 | 0.89 | TDP1 (0.53) | TDP1LMNAEGLN1ALKBH5SUCNR1 | |
| Adipic Acid SCHEMBL346488 | 0.89 | LMNA (0.58) | TDP1LMNAOR51E2ALDH1A1SLC22A6 | |
| Glutarate SCHEMBL28304978 | 0.89 | SLC22A6 (0.58) | TDP1LMNAOR51E2CAMK2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980252-A | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2022-01-28 | — | — | CN | claimed |
| CN-113980252-B | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2023-09-01 | — | — | CN | disclosed |
| CN-113980252-A | Continuous production method of modified poly (butylene succinate) | 上海师范大学 | 2022-01-28 | — | — | CN | disclosed |