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Sugi Predict / Compounds / SCHEMBL29364504

SCHEMBL29364504

SCHEMBL29364504

CC(C)[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)C(C)(C)NC(=O)[C@@H](N)Cc1c[nH]cn1)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 20/20 0.66
▸ SCTR P47872 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367013 1.00 GLP1R (0.66) GLP1RSCTR
SCHEMBL29367867 0.94 GLP1R (0.58) GLP1RSCTR
SCHEMBL29364498 0.94 GLP1R (0.58) GLP1RSCTR
SCHEMBL29367449 0.94 GLP1R (0.58) GLP1RSCTR
SCHEMBL29367002 0.94 GLP1R (0.58) GLP1RSCTR
SCHEMBL30576560 0.94 GLP1R (0.66) GLP1RSCTR
SCHEMBL29554395 0.93 GLP1R (0.63) GLP1RSCTR
SCHEMBL31058454 0.93 GLP1R (0.71) GLP1RSCTR
SCHEMBL31058452 0.93 GLP1R (0.71) GLP1RSCTR
SCHEMBL31406266 0.93 GLP1R (0.75) GLP1RSCTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022111370-A1 GLP-1/GLUCAGON RECEPTOR DUAL-AGONIST AND APPLICATION THEREOF 江苏师范大学 2022-06-02 — — WO claimed
CN-114349828-A GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-04-15 — — CN claimed
CN-114349828-B GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2023-12-08 — — CN disclosed
WO-2022111370-A1 GLP-1/GLUCAGON RECEPTOR DUAL-AGONIST AND APPLICATION THEREOF 江苏师范大学 2022-06-02 — — WO disclosed
CN-114349828-A GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-04-15 — — CN disclosed
CN-112409460-B GLP-1/glucagon receptor dual agonist and application thereof 江苏师范大学 2022-02-01 — — CN disclosed
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