Ditolylguanidine

Ditolylguanidine

SCHEMBL29364709

Cc1ccccc1N=C(N)Nc1ccccc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 18/20 1.00
GRIN2D O15399 14/20 1.00
GRIN3B O60391 14/20 1.00
GRIN1 Q05586 14/20 1.00
GRIN2A Q12879 14/20 1.00
GRIN2B Q13224 14/20 1.00
GRIN2C Q14957 14/20 1.00
GRIN3A Q8TCU5 14/20 1.00
MEN1 O00255 1/20 1.00
PABPC1 P11940 1/20 1.00
ALOX15 P16050 1/20 1.00
TSHR P16473 1/20 1.00
KMT2A Q03164 1/20 1.00
EBP Q15125 1/20 1.00
TMEM97 Q5BJF2 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ditolylguanidine SCHEMBL80339 1.00 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Ditolylguanidine SCHEMBL158674 1.00 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Ditolylguanidine SCHEMBL3388414 1.00 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Ditolylguanidine SCHEMBL8862769 0.98 SIGMAR1 (0.97) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8873081 0.87 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8875387 0.87 SIGMAR1 (0.78) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8874196 0.84 SIGMAR1 (0.81) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8873792 0.84 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL14861883 0.83 SIGMAR1 (0.78) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL8874645 0.83 SIGMAR1 (1.00) SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 660 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079768-A Method for selectively and efficiently depolymerizing and recycling PET in waste blended fabric 2026-05-26 CN claimed
EP-4739514-A1 RUBBER MIXTURES CONTAINING POLYETHYLENEIMINE AND AT LEAST ONE PROCESSING AID CONTAINING AT LEAST ONE FATTY ACID LANXESS Deutschland GmbH (DE) 2026-05-13 EP claimed
EP-3898825-B1 CAPSULES COMPRISING VULCANISATION ACCELERANT AGENTS, THEIR PREPARATION AND USE IN THE VULCANISATION OF ELASTOMERIC COMPOUNDS FOR TYRES PIRELLI (IT) 2026-04-01 EP claimed
US-12466918-B2 Mixtures containing an aminically crosslinkable rubber and polyethyleneimine LANXESS DEUTSCHLAND GMBH (DE) 2025-11-11 US claimed
WO-2025229665-A1 PREPARATION OF GRAPHENE-RUBBER MASTERBATCH CEAT LIMITED (IN) 2025-11-06 WO claimed
CN-120059146-A Method for preparing bio-based polyester-carbonate based on bio-based dicarboxylic acid carbonate 沈阳工业大学 2025-05-30 CN claimed
CN-120005340-A Ageing-resistant acrylate rubber compound and preparation method thereof 九江杜威橡胶科技有限公司 2025-05-16 CN claimed
CN-119931194-A Self-lubricating rubber material and preparation method thereof 昆山力普电子橡胶有限公司 2025-05-06 CN claimed
WO-2025012012-A1 RUBBER MIXTURES CONTAINING POLYETHYLENEIMINE AND AT LEAST ONE PROCESSING AID CONTAINING AT LEAST ONE FATTY ACID LANXESS DEUTSCHLAND GMBH (DE) 2025-01-16 WO claimed
EP-4488074-A1 RUBBER MIXTURES CONTAINING POLYETHYLENIMINE AND AT LEAST ONE PROCESSING AID CONTAINING AT LEAST ONE FATTY ACID LANXESS Deutschland GmbH (DE) 2025-01-08 EP claimed
WO-2022165496-A1 MULTILAYER RUBBER HOSE CONTITECH USA, INC. (US) 2022-08-04 WO claimed
CN-113150409-B Rubber composition for all-steel radial tire body and preparation method thereof 中国科学院长春应用化学研究所 2022-07-15 CN claimed
EP-4021972-A1 MIXTURES CONTAINING AN AMINICALLY CROSSLINKABLE RUBBER AND POLYETHYLENE IMINE LANXESS Deutschland GmbH (DE) 2022-07-06 EP claimed
EP-4017253-A1 RNA-BASED THERAPEUTIC METHODS TO PROTECT ANIMALS AGAINST PATHOGENIC BACTERIA AND / OR PROMOTE BENEFICIAL EFFECTS OF SYMBIOTIC AND COMMENSAL BACTERIA CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2022-06-29 EP claimed
EP-3983475-A1 THERMALLY EXPANDABLE COMPOSITIONS COMPRISING A CHEMICAL BLOWING AGENT Sika Technology AG (CH) 2022-04-20 EP claimed
CN-114316400-A Rubber cloth-sandwiched diaphragm for hydrogen fuel cell and preparation method thereof 宁波泰科威橡胶科技有限公司 2022-04-12 CN claimed
CN-114292513-A High-tolerance intake manifold diaphragm and preparation method thereof 宁波泰科威橡胶科技有限公司 2022-04-08 CN claimed
CN-114286841-A Mixture comprising amine-crosslinkable rubber and polyethyleneimine 朗盛德国有限责任公司 2022-04-05 CN claimed
CN-111533970-B Mildew-proof antibacterial rubber and plastic product and preparation method thereof 神州节能科技集团有限公司 2022-03-11 CN claimed
CN-113999473-A High-temperature-resistant acrylate rubber and preparation method thereof 重庆长安汽车股份有限公司 2022-02-01 CN claimed