Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 16/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.61 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.57 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.55 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.55 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | ROS1 | P08922 | 1/20 | 0.55 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodotubercidin SCHEMBL29383008 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL16978206 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL13021361 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL319225 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL29375718 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL8328935 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL2786488 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL12652819 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL12505209 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 | |
| Iodotubercidin SCHEMBL12618424 | 0.90 | ADK (0.83) | ADKSLC29A1DOT1LNPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220233566-A1 | NOVEL CARBONATE COMPOUND HAVING PYRROLOPYRIMIDINE SKELETON OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2022-07-28 | — | — | US | disclosed |
| CN-114008064-A | Novel phosphate ester compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-02-01 | — | — | CN | disclosed |
| CN-113993877-A | Novel carbonate compound having pyrrolopyrimidine skeleton or pharmaceutically acceptable salt thereof | 大鹏药品工业株式会社 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220233566-A1 | NOVEL CARBONATE COMPOUND HAVING PYRROLOPYRIMIDINE SKELETON OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | TYMP, SLC20A1, MGMT | ADK 2048/4885SLC29A1 20/4885DOT1L 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.