Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 1.00 |
| ▸ | CCNB2 | O95067 | 19/20 | 1.00 |
| ▸ | CDK1 | P06493 | 19/20 | 1.00 |
| ▸ | CCNB1 | P14635 | 19/20 | 1.00 |
| ▸ | CCNB3 | Q8WWL7 | 19/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 17/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 17/20 | 1.00 |
| ▸ | CCNA2 | P20248 | 3/20 | 1.00 |
| ▸ | CDK2 | P24941 | 3/20 | 1.00 |
| ▸ | CCNA1 | P78396 | 3/20 | 1.00 |
| ▸ | CCNT1 | O60563 | 2/20 | 1.00 |
| ▸ | CDK9 | P50750 | 2/20 | 1.00 |
| ▸ | GSK3A | P49840 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | CDC7 | O00311 | 1/20 | 1.00 |
| ▸ | PLK4 | O00444 | 1/20 | 1.00 |
| ▸ | CHEK1 | O14757 | 1/20 | 1.00 |
| ▸ | AURKA | O14965 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kenpaullone SCHEMBL30789744 | 1.00 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Kenpaullone SCHEMBL79889 | 1.00 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL5688213 | 0.90 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL30319776 | 0.90 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL5688155 | 0.90 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL30319757 | 0.90 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL5689156 | 0.86 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL30319766 | 0.86 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Paullone SCHEMBL3178594 | 0.85 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 | |
| Paullone SCHEMBL29407267 | 0.85 | CCNB2 (1.00) | GSK3BCCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603913-A | Inducer composition for preparing induced pluripotent stem cells and application thereof | 浙江霍德生物工程有限公司 | 2024-02-27 | — | — | CN | claimed |
| US-20230183323-A1 | METHODS FOR PREVENTING, REVERSING OR TREATING A COVID-19 INFECTION | BROWN UNIVERSITY | 2023-06-15 | — | — | US | claimed |
| CN-113201560-B | Method for establishing repair type multipotent kidney precursor stem cell library | 北京起源爱心生物科技有限公司 | 2023-05-30 | — | — | CN | claimed |
| CN-108431209-B | Derived and mature hepatocyte types of liver stem cells and uses thereof | 新加坡科技研究局 | 2023-02-10 | — | — | CN | claimed |
| CN-114430774-A | Organoid mesoderm lineage diversification | 儿童医院医学中心 | 2022-05-03 | — | — | CN | claimed |
| US-12570957-B2 | Isolated naive pluripotent stem cells and methods of generating same | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2026-03-10 | — | — | US | disclosed |
| US-20260028583-A1 | ISOLATED NAIVE PLURIPOTENT STEM CELLS AND METHODS OF GENERATING SAME | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2026-01-29 | — | — | US | disclosed |
| WO-2025217202-A1 | BILE DUCT ORGANOID | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-10-16 | — | — | WO | disclosed |
| US-12318391-B2 | Methods and compositions for the prevention and treatment of hearing loss | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2025-06-03 | — | — | US | disclosed |
| EP-4387622-B1 | HALOPERIDOL FOR USE IN THE TREATMENT OF SPINAL MUSCULAR ATROPHY | UNIV VALENCIA (ES) | 2025-05-28 | — | — | EP | disclosed |
| CN-119868371-A | Application of Kenparone in preparation of medicine for relieving unilateral ureteral ligation induced kidney fibrosis | 江苏省人民医院（南京医科大学第一附属医院） | 2025-04-25 | — | — | CN | disclosed |
| WO-2025072803-A1 | NTRK2 SIGNALING-MEDIATED ALVEOLAR CAPILLARY INJURY AND REPAIR | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-04-03 | — | — | WO | disclosed |
| CN-114364790-A | Method for producing T cell | 艾达普特免疫有限公司 | 2022-04-15 | — | — | CN | disclosed |
| CN-114341349-A | Hematopoietic induction medium | 艾达普特免疫有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114269904-A | Generation of T cells from RAG-inactivated iPSCs | 艾达普特免疫有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114269906-A | Method for producing hematopoietic progenitor cells from pluripotent stem cells | 艾达普特免疫有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114164167-A | Cell culture platform for single cell sorting and enhanced IPSC reprogramming | 菲特治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114127266-A | Selective differentiation regulating method for musculoskeletal system stem cells | 雪拉托兹治疗株式会社 | 2022-03-01 | — | — | CN | disclosed |
| CN-114026222-A | Method for producing brain organoid | 学校法人庆应义塾 | 2022-02-08 | — | — | CN | disclosed |
| CN-113993528-A | Method for producing living body-like tissue structure | 千纸鹤治疗公司 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260028583-A1 | ISOLATED NAIVE PLURIPOTENT STEM CELLS AND METHODS OF GENERATING SAME | PRKD3, GSK3B, GSK3A | GSK3B 2/4885CCNB2 3045/4885CDK1 839/4885 |
| US-12570957-B2 | Isolated naive pluripotent stem cells and methods of generating same | GSK3B, EZH2, GSK3A | GSK3B 1/4885CCNB2 2866/4885CDK1 761/4885 |
| US-12318391-B2 | Methods and compositions for the prevention and treatment of hearing loss | CDK2, CDK5, CDK20 | GSK3B 108/4885CCNB2 30/4885CDK1 6/4885 |
| US-20230183323-A1 | METHODS FOR PREVENTING, REVERSING OR TREATING A COVID-19 INFECTION | CHI3L1, CHI3L2, ACE2 | GSK3B 2653/4885CCNB2 4333/4885CDK1 4091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.