⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111337 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL25301697 | 0.96 | — | — | |
| SCHEMBL1456362 | 0.86 | ALDH1A1 (0.46) | — | |
| Formic Acid SCHEMBL29166004 | 0.80 | GAA (0.42) | — | |
| SCHEMBL30425828 | 0.80 | — | — | |
| SCHEMBL29708474 | 0.80 | — | — | |
| SCHEMBL38738 | 0.80 | — | — | |
| SCHEMBL428878 | 0.80 | — | — | |
| SCHEMBL646579 | 0.80 | — | — | |
| SCHEMBL29860455 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 284 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120535467-B | Synthesis method of amazinmide bulk drug | 安徽峆一药业股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-121021404-B | Synthesis process of high-purity sulfachloropyridazine sodium | 寿光富康制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-120092001-A | Method for producing ALOGABAT | 豪夫迈·罗氏有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-119977894-A | Industrial preparation method of high-purity 3, 6-dichloro-4-isopropyl pyridazine | 南京方生和医药科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119613758-A | Zn-MOF material, preparation method thereof and application thereof in congo red dye adsorption | 南昌大学 | 2025-03-14 | — | — | CN | claimed |
| CN-119504714-A | Rasemet-teh preparation method of herba Luo | 河北科技大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119118927-A | Synthesis method of 3-chloro-6-methylpyridazine | 上海毕得医药科技股份有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-118742540-A | Preparation method of pyridazinone derivative and intermediate thereof | 西藏海思科制药有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118561764-A | Preparation method and crystal form of PDE4 inhibitor clobiprofen | 兰晟生物医药(苏州)有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-117897244-A | Metal paste for bonding, bonded body, and method for producing same | 株式会社力森诺科 | 2024-04-16 | — | — | CN | claimed |
| CN-113277984-B | Method for preparing 3, 6-dichloropyridazine-4-alcohol | 武威广达科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-113666876-B | Production process of sulfachloropyridazine | 佛山市南海北沙制药有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-114671813-B | Photosensitizer with fluorescence imaging and photodynamic gram-positive bacteria killing activities as well as preparation method and application thereof | 内蒙古大学 | 2023-09-05 | — | — | CN | claimed |
| CN-112898198-B | Nitrogen-containing aromatic heterocyclic nitro compound and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-111349119-B | Pterene pyridazine octadentate double platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-07-26 | — | — | CN | claimed |
| CN-114671813-A | Photosensitizer with activities of fluorescence imaging and photodynamic killing of gram-positive bacteria and preparation method and application thereof | 内蒙古大学 | 2022-06-28 | — | — | CN | claimed |
| CN-114516840-A | Preparation method of 2- [ (6-chloropyridazin-3-yl) thio ] -N, N-diethylacetamide | 安徽修一制药有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-112645936-B | Substituted pyridazinone compound and use thereof | 山东第一医科大学(山东省医学科学院) | 2022-03-01 | — | — | CN | claimed |
| CN-114105884-A | Preparation method and crystal form of PDE4 inhibitor clobiplane | 兰晟生物医药(苏州)有限公司 | 2022-03-01 | — | — | CN | claimed |
| EP-4746964-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| CN-122071610-A | Resin composition and use thereof | 台燿科技股份有限公司 | 2026-05-22 | — | — | CN | disclosed |
| CN-122036699-A | THR-beta modulators and methods of use thereof | 阿利戈斯治疗公司 | 2026-05-15 | — | — | CN | disclosed |
| CN-122055400-A | Composition, prepreg and metal-clad laminate | ＡＧＣ株式会社 | 2026-05-15 | — | — | CN | disclosed |
| CN-122029231-A | Resin composition, prepreg, metal-clad laminate, and method for producing same | ＡＧＣ株式会社 | 2026-05-12 | — | — | CN | disclosed |
| CN-112805005-B | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-121021404-B | Synthesis process of high-purity sulfachloropyridazine sodium | 寿光富康制药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-121021404-B | Synthesis process of high-purity sulfachloropyridazine sodium | 寿光富康制药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4725021-A1 | METHOD AND SYSTEM FOR CALCULATING MASS FLOW AND ESTIMATING SUSTAINABILITY METRICS IN CHEMICAL SYNTHESIS | Merck Patent GmbH (DE) | 2026-04-15 | — | — | EP | disclosed |
| EP-4720065-A1 | PRMT5 INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-04-08 | — | — | EP | disclosed |
| WO-2026046976-A1 | PYRAZOLOPYRIDINE PHOSPHATE ESTERS FOR MODULATING SALT-INDUCIBLE KINASE (SIK) | F. HOFFMANN-LA ROCHE AG (CH) | 2026-03-05 | — | — | WO | disclosed |
| EP-4698520-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | Gandeeva Therapeutics, Inc. (US) | 2026-02-25 | — | — | EP | disclosed |
| CN-121517367-A | Preparation method of 3, 6-dichloropyridazine | 上海筑裕新材料科技有限公司 | 2026-02-13 | — | — | CN | disclosed |
| CN-121517367-A | Preparation method of 3, 6-dichloropyridazine | 上海筑裕新材料科技有限公司 | 2026-02-13 | — | — | CN | disclosed |
| EP-4680601-A1 | PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES | Sanofi (FR) | 2026-01-21 | — | — | EP | disclosed |
| US-12522597-B2 | Methods and compositions for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2026-01-13 | — | — | US | disclosed |
| CN-119613758-B | Zn-MOF material, preparation method thereof and application thereof in congo red dye adsorption | 南昌大学 | 2025-12-16 | — | — | CN | disclosed |
| CN-121021404-A | Synthesis process of high-purity sulfachloropyridazine sodium | 寿光富康制药有限公司 | 2025-11-28 | — | — | CN | disclosed |
| EP-4642773-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| EP-4634161-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Tenvie Therapeutics Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| CN-120718007-A | Rameiti preparation method of herba Luo | 沈阳药科大学 | 2025-09-30 | — | — | CN | disclosed |
| CN-119118927-B | Synthesis method of 3-chloro-6-methylpyridazine | 上海毕得医药科技股份有限公司 | 2025-09-26 | — | — | CN | disclosed |
| CN-120463650-A | Industrial preparation method of 3, 6-dichloropyridazine | 重庆工业职业技术学院 | 2025-08-12 | — | — | CN | disclosed |
| CN-120463650-A | Industrial preparation method of 3, 6-dichloropyridazine | 重庆工业职业技术学院 | 2025-08-12 | — | — | CN | disclosed |
| EP-4581032-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2025-07-09 | — | — | EP | disclosed |
| US-20250215016-A1 | ISOXAZOLE-HETEROCYCLIC DERIVATIVE, PHARMACEUTICAL COMPOSITION AND USE | Shanghai SIMR Biotechnology Co., Ltd (CN) | 2025-07-03 | — | — | US | disclosed |
| WO-2025137605-A1 | COMPOUNDS FOR TARGETED DEGRADATION OF PROTO-ONCOGENE TYROSINE PROTEIN KINASE RECEPTOR | C4 THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-115667259-B | Fused ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2025-06-17 | — | — | CN | disclosed |
| CN-120136892-A | Pyridazine anthracene luminescent material and application thereof | 烟台九目化学股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120091819-A | Small molecule inhibitors of mammalian SLC6A19 function | 杰那医疗公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-120092001-A | Method for producing ALOGABAT | 豪夫迈·罗氏有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115850346-B | Pinene pyridazine tetradentate platinum (II) and palladium (II) complex based on intramolecular hydrogen bond and preparation method and application thereof | 南京邮电大学 | 2025-05-16 | — | — | CN | disclosed |
| CN-119977894-A | Industrial preparation method of high-purity 3, 6-dichloro-4-isopropyl pyridazine | 南京方生和医药科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119894879-A | Tyrosine kinase 2 inhibitors and uses thereof | 渤健马萨诸塞州股份有限公司 | 2025-04-25 | — | — | CN | disclosed |
| CN-112424197-B | Difluoromethyl-phenyltriazoles as modulators of GABA receptors | 勃林格殷格翰国际公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119859358-A | Resin composition and use thereof | 台燿科技股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| CN-119836453-A | Polymer, composition, cured product, and display element | JSR株式会社 | 2025-04-15 | — | — | CN | disclosed |
| CN-119822554-A | Treatment method of phosphorus-containing wastewater generated in preparation process of sulfonamide compound | 佛山市南海北沙制药有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119798221-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-119732956-A | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| CN-119638696-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-119613758-A | Zn-MOF material, preparation method thereof and application thereof in congo red dye adsorption | 南昌大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-113454069-B | 1,2, 4-Triazine-3, 5-dione compound, and preparation method and application thereof | 昆药集团股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119613758-A | Zn-MOF material, preparation method thereof and application thereof in congo red dye adsorption | 南昌大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-119548987-A | Nanofiltration membrane preparation method, nanofiltration membrane prepared by method and application of nanofiltration membrane | 沃顿科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119552152-A | Thyroid hormone receptor agonists | 益方生物科技(上海)股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119546586-A | Modulators of NLRP3 inflammatory corpuscles and related products and methods | 纽摩拉治疗公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115703765-B | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119528905-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-113784957-B | NLRP3 inflammatory corpuscle inhibitor | 诺华股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119504714-A | Rasemet-teh preparation method of herba Luo | 河北科技大学 | 2025-02-25 | — | — | CN | disclosed |
| CN-113490668-B | Compounds and compositions for the treatment of diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-119462517-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-112261970-B | 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family zinc finger 2 (IKZF 2) dependent diseases | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-116134027-B | Heteroaryl-substituted 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2025017078-A1 | NEW PYRAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |
| CN-119317656-A | Polymer, composition, cured product, laminate, and electronic component | JSR株式会社 | 2025-01-14 | — | — | CN | disclosed |
| CN-119301116-A | NLRP3 modulators | 祖玛珍生物科学有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119300833-A | Novel compounds | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119264128-A | Thiadiazole and pyridazine parent nucleus compound, preparation method and pharmaceutical application thereof | 中国医学科学院药物研究所 | 2025-01-07 | — | — | CN | disclosed |
| CN-119241499-A | 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-113727972-B | Novel hydrazone derivatives having terminal amine groups substituted with aryl or heteroaryl groups and use thereof | 韩国科学技术研究院 | 2024-12-27 | — | — | CN | disclosed |
| CN-119212992-A | Nicotinic acetylcholine receptor ligands | 菲利普莫里斯生产公司 | 2024-12-27 | — | — | CN | disclosed |
| WO-2024256360-A1 | METHOD AND SYSTEM FOR CALCULATING MASS FLOW AND ESTIMATING SUSTAINABILITY METRICS IN CHEMICAL SYNTHESIS | MERCK PATENT GMBH (DE) | 2024-12-19 | — | — | WO | disclosed |
| CN-118159524-B | Synthesis method of intermediate of imidazo [1,2-b ] pyridazine compound | 和记黄埔医药（上海）有限公司 | 2024-12-17 | — | — | CN | disclosed |
| CN-119118927-A | Synthesis method of 3-chloro-6-methylpyridazine | 上海毕得医药科技股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119118927-A | Synthesis method of 3-chloro-6-methylpyridazine | 上海毕得医药科技股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-119080754-A | As alpha 5-GABAAHeterocyclic compounds of receptor modulators and uses thereof | 武汉人福创新药物研发中心有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2024245412-A1 | PRMT5 INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-12-05 | — | — | WO | disclosed |
| CN-119019425-A | Alpha 5-GABAAHeterocyclic compounds as receptor modulators | 武汉人福创新药物研发中心有限公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-119032081-A | Process for preparing various substituted cyanocyclopropyl-heteroarenes or arenes | 先正达农作物保护股份公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-112739692-B | Thyroid hormone receptor agonists | 益方生物科技(上海)股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-114981256-B | Single-ring agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2024-11-08 | — | — | CN | disclosed |
| EP-4457225-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2024-11-06 | — | — | EP | disclosed |
| EP-4452943-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | Jnana Therapeutics Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-118843625-A | Heterocyclically substituted 1,3, 4-thiadiazole and pyridazine compounds and methods of use thereof | 亚根达医疗公司 | 2024-10-25 | — | — | CN | disclosed |
| WO-2024220708-A1 | RAF-MEK PROTEIN COMPLEX MODULATORS AND METHODS OF USE THEREOF | GANDEEVA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-118829628-A | Small molecule inhibitors of mammalian SLC6A19 function | 杰那医疗公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-118791426-A | (R) -glutarimide CRBN ligands and methods of use | 百济神州有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118786117-A | Heterocyclic amides and methods of use thereof | 亚根达医疗公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-118742540-A | Preparation method of pyridazinone derivative and intermediate thereof | 西藏海思科制药有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118702672-A | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2024188994-A1 | PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES | SANOFI (FR) | 2024-09-19 | — | — | WO | disclosed |
| EP-4430052-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | Nurix Therapeutics, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-111333627-B | Substituted 2-hydro-pyrazole derivatives as anticancer agents | 正大天晴药业集团股份有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-114555592-B | 2-Azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2024-09-06 | — | — | CN | disclosed |
| WO-2024182747-A2 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |
| CN-118598858-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-116283789-B | Pyridazine-containing chalcone derivative and preparation method and application thereof | 贵州大学 | 2024-09-03 | — | — | CN | disclosed |
| CN-118591534-A | Novel benzimidazole pyridine derivatives | 豪夫迈·罗氏有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118580191-A | Intermediate for preparing imidazo [1,2-b ] pyridazine compounds | 和记黄埔医药（上海）有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-118561764-A | Preparation method and crystal form of PDE4 inhibitor clobiprofen | 兰晟生物医药(苏州)有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-118541365-A | Antagonists of muscarinic acetylcholine receptor M4 | 范德堡大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-108368040-B | Diaryl monocyclic beta-lactam compounds and methods for their use in the treatment of bacterial infections | 默沙东有限责任公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-115947691-B | Pyridazine sulfone derivative and application thereof | 四川大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-118475571-A | Degradation of Bruton Tyrosine Kinase (BTK) by conjugation of BTK inhibitors to E3 ligase ligands and methods of use | 百济神州有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118451078-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2024-08-06 | — | — | CN | disclosed |
| CN-118388413-A | Method for preparing 6- (4-amino-2, 6-dichlorophenoxy) -4-isopropyl pyridazin-3 (2H) -ketone | 成都伊诺达博医药科技有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-112055711-B | Cyclohexylic acid triazolazine as LPA antagonist | 百时美施贵宝公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-115466223-B | Heterocyclic benzamide compound and application thereof in promoting plant growth and development | 南方科技大学 | 2024-07-19 | — | — | CN | disclosed |
| CN-118355004-A | Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives | 勃林格殷格翰动物保健有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-115916777-B | ATX inhibitor and preparation method and application thereof | 苏州爱科百发生物医药技术有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-116143757-B | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024141444-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-07-04 | — | — | WO | disclosed |
| CN-115335369-B | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118265701-A | Pyridazine derivatives as inhibitors of NLRP3 | 豪夫迈·罗氏有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2024130166-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-113412112-B | Organophosphorus substituted compounds as c-MET inhibitors and therapeutic uses thereof | 贝达医药公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-114072390-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118159524-A | Synthesis method of intermediate of imidazo [1,2-b ] pyridazine compound | 和记黄埔医药（上海）有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-114478361-B | Method for preparing aza-arene compound by coupling reaction without metal catalysis | 浙江工业大学 | 2024-06-07 | — | — | CN | disclosed |
| CN-117946307-B | Pyridazine resin, preparation method thereof and cobalt removal method of lithium battery recovery liquid | 江苏海普功能材料有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118047654-A | Process for preparing aryl halides starting from aromatic amines | 黑龙江立科新材料有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115335050-B | Compounds and compositions for treating skin disorders | 卡玛瑞制药有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-115872976-B | Quinoline derivative, pharmaceutical composition containing quinoline derivative and application of pharmaceutical composition | 中国药科大学 | 2024-05-14 | — | — | CN | disclosed |
| WO-2024094150-A1 | NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-05-10 | — | — | WO | disclosed |
| CN-118005615-A | Pyridazine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117964557-A | Preparation method of rosuvastatin intermediate | 重庆药友制药有限责任公司 | 2024-05-03 | — | — | CN | disclosed |
| EP-4359403-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BeiGene Switzerland GmbH (CH) | 2024-05-01 | — | — | EP | disclosed |
| CN-117946307-A | Pyridazine resin, preparation method thereof and cobalt removal method of lithium battery recovery liquid | 江苏海普功能材料有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2024084491-A1 | PROCESS FOR SYNTHESIS OF RES METIROM AND ITS INTERMEDIATES THEREOF | MEHTA NILESH VIPINCHANDRA (IN) | 2024-04-25 | — | — | WO | disclosed |
| CN-117897244-A | Metal paste for bonding, bonded body, and method for producing same | 株式会社力森诺科 | 2024-04-16 | — | — | CN | disclosed |
| CN-117843621-A | Novel pyridazine compound, and pharmaceutical composition and application thereof | 南京知和医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117843521-A | Compound serving as thyroid hormone beta receptor agonist as well as preparation method and application thereof | 中国药科大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-117836299-A | Novel bifunctional heterocyclic compounds with Bruton tyrosine kinase decomposition via ubiquitin proteasome pathway and uses thereof | 韩国化学研究院 | 2024-04-05 | — | — | CN | disclosed |
| CN-113544191-B | Laminate for high-frequency circuit, method for producing same, flexible printed board, B-stage sheet, and laminate roll | JSR株式会社 | 2024-03-29 | — | — | CN | disclosed |
| CN-117756722-A | Synthesis method of rosuvastatin intermediate | 奥锐特药业(天津)有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-115028637-B | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117751115-A | Compounds, compositions, and methods of treating cancer | 热点治疗公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117730081-A | Substituted spirocyclic derivatives | 詹森药业有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024053722-A1 | POLYMER, COMPOSITION, CURED PRODUCT, AND DISPLAY ELEMENT | JSR株式会社 | 2024-03-14 | — | — | WO | disclosed |
| EP-4334320-A1 | SUBSTITUTED SPIRO DERIVATIVES | JANSSEN Pharmaceutica NV (BE) | 2024-03-13 | — | — | EP | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2024046457-A1 | TRIAZINE COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-03-07 | — | — | WO | disclosed |
| CN-111194215-B | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117616021-A | (R) -glutarimide CRBN ligands and methods of use | 百济神州有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-113861407-B | Polymer, composition, and molded article | JSR株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-117534670-A | Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders | 加拉帕戈斯股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-111499615-B | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-114072396-B | Quinoline and cinnoline derivatives as DNA-PK inhibitors | 南京明德新药研发有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-111491920-B | Antagonists of muscarinic acetylcholine receptor M4 | 范德比尔特大学 | 2024-01-30 | — | — | CN | disclosed |
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |
| CN-112351984-B | Tetrahydrobenzofuro [2.3-c ] pyridine and beta-carboline compounds for the treatment, alleviation or prevention of conditions associated with Tau aggregate | AC免疫有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117285525-A | Novel isoxazolyl ether derivatives as GABAA alpha 5PAM | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-116969955-B | [1,2,4] triazole [4,3-b ] pyridazine compound and preparation method and application thereof | 中国药科大学 | 2023-12-19 | — | — | CN | disclosed |
| EP-4288442-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | Faxian Therapeutics, LLC (US) | 2023-12-13 | — | — | EP | disclosed |
| CN-117164522-A | Aminomide oxidation impurity and preparation method thereof | 安徽峆一药业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117126133-A | Compound and application thereof | 中国海洋大学 | 2023-11-28 | — | — | CN | disclosed |
| CN-117120435-A | ABHD6 antagonists | 小野药品工业株式会社 | 2023-11-24 | — | — | CN | disclosed |
| CN-117015378-A | Small molecule inhibitors of mammalian SLC6A19 function | 杰那医疗公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-111225916-B | Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders | 加拉帕戈斯股份有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-111170991-B | Antiproliferative compounds and methods of synthesis thereof | 细胞基因公司 | 2023-10-31 | — | — | CN | disclosed |
| CN-116940563-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-116917376-A | Polymer, composition, cured product, laminate, and electronic component | JSR株式会社 | 2023-10-20 | — | — | CN | disclosed |
| CN-116888115-A | Difluoromethyl-pyridin-2-yl triazoles | 勃林格殷格翰国际有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-109923113-B | Isoxazolyl ether derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113277984-B | Method for preparing 3, 6-dichloropyridazine-4-alcohol | 武威广达科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113277984-B | Method for preparing 3, 6-dichloropyridazine-4-alcohol | 武威广达科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113277984-B | Method for preparing 3, 6-dichloropyridazine-4-alcohol | 武威广达科技有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-113666876-B | Production process of sulfachloropyridazine | 佛山市南海北沙制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-113666876-B | Production process of sulfachloropyridazine | 佛山市南海北沙制药有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2023183757-A2 | ORTHOGONAL FUNCTIONALIZATION OF BRIDGE-SUBSTITUTED BCPS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-09-28 | — | — | WO | disclosed |
| CN-111788182-B | Muscarinic acetylcholine receptor M 4 Antagonists of (2) | 范德堡大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-116768802-A | Synthesis method of rismiterol | 杭州科巢生物科技有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113087704-B | Preparation method and application of protein degradation agent compound | 上海济煜医药科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-114671813-B | Photosensitizer with fluorescence imaging and photodynamic gram-positive bacteria killing activities as well as preparation method and application thereof | 内蒙古大学 | 2023-09-05 | — | — | CN | disclosed |
| WO-2022268052-A9 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-08-17 | — | — | WO | disclosed |
| CN-113956208-B | Aryl heterocyclic derivative and synthesis method thereof | 郑州大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-116583283-A | CDK inhibitors and their use as pharmaceuticals | 普莱鲁德疗法有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | GALAPAGOS NV (BE) | 2023-08-08 | — | — | US | disclosed |
| CN-110914242-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116410140-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-111556871-B | 1H-pyrazolo [4,3-b ] pyridines as PDE1 inhibitors | H.隆德贝克有限公司 | 2023-07-07 | — | — | CN | disclosed |
| WO-2023125908-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |
| CN-116390917-A | MRGX2 antagonists | 葛兰素史密斯克莱知识产权发展有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-107973809-B | Macrocyclic compounds as factor XIA inhibitors | 百时美施贵宝公司 | 2023-06-30 | — | — | CN | disclosed |
| WO-2023122267-A2 | SMALL MOLECULE INHIBITORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| CN-116283789-A | Pyridazine-containing chalcone derivative and preparation method and application thereof | 贵州大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-111566103-B | Aminoimidazopyrazines as kinase inhibitors | 百时美施贵宝公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4192823-A1 | DIFLUOROMETHYL-PYRIDIN-2-YL TRIAZOLES | Boehringer Ingelheim International GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-111819173-B | CD73 inhibitors | 伊莱利利公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-116209706-A | Prepreg, metal-clad laminate, and printed wiring board | JSR株式会社 | 2023-06-02 | — | — | CN | disclosed |
| CN-111909137-B | Pyridazinone derivative and application thereof | 深圳微芯生物科技股份有限公司 | 2023-05-30 | — | — | CN | disclosed |
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| CN-116143757-A | Multifunctional compound, composition and application of degradable BTK kinase | 杭州和正医药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-111253404-B | Nitrogen-containing heterocyclic compound and composition, preparation method and application thereof | 上海医药集团股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-114276331-B | 4-aminopiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-05-23 | — | — | CN | disclosed |
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| CN-116134027-A | Heteroaryl-substituted 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-116134029-A | Oxo-nitrogen ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| EP-4172148-A1 | PROCESS FOR THE MANUFACTURE OF 1,4-DISUBSTITUTED PYRIDAZINE COMPOUNDS | Novartis AG (CH) | 2023-05-03 | — | — | EP | disclosed |
| CN-116056709-A | Pyridazinone compounds | 益方生物科技(上海)股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-115947691-A | Pyridazine sulfone derivative and application thereof | 四川大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-112898198-B | Nitrogen-containing aromatic heterocyclic nitro compound and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-115916757-A | Process for producing 1, 4-disubstituted pyridazine compound | 诺华股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115867279-A | Novel oxopyridazinyl-phenyl-carbohydrazone acyldinitrile compounds and use thereof | 韩国科学技术研究院 | 2023-03-28 | — | — | CN | disclosed |
| WO-2023034836-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| CN-115715287-A | Substituted N- (methyl-d 3) pyridazine-3-carboxamide or N- (methyl-d 3) -nicotinamide compounds as IL-12, IL-23 and/or IFN alpha modulators | 百时美施贵宝公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| CN-115703765-A | Substituted triazole derivative, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2023-02-17 | — | — | CN | disclosed |
| WO-2022268052-A1 | (R) -GLUTARIMIDE CRBN LIGANDS AND METHODS OF USE | BEIGENE, LTD. (KY) | 2022-12-29 | — | — | WO | disclosed |
| CN-115466223-A | Heterocyclic benzamide compound and application thereof in promoting plant growth and development | 南方科技大学 | 2022-12-13 | — | — | CN | disclosed |
| WO-2022237627-A1 | SUBSTITUTED SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2022-11-17 | — | — | WO | disclosed |
| CN-115335369-A | GEM-disubstituted piperidine melanocortin subtype-2 receptor (MC 2R) antagonists and uses thereof | 克林提克斯医药股份有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-110494431-B | Azacyclo derivative, preparation method and medical application thereof | 苏州浦合医药科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-111100074-B | Pyridazine hydrazone derivative and preparation method and application thereof | 南华大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-113278013-B | 2, 6-disubstituted 1,2, 4-triazine-3, 5-diketone compound and preparation method and application thereof | 昆药集团股份有限公司 | 2022-09-23 | — | — | CN | disclosed |
| CN-115087657-A | LIN28 inhibitor and method of use thereof | 加利福尼亚大学董事会 | 2022-09-20 | — | — | CN | disclosed |
| CN-113121562-B | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-115028637-A | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-115028636-A | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-113105475-B | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-114981256-A | Single-ring agonists of the interferon gene stimulator STING | 斯克里普斯研究学院 | 2022-08-30 | — | — | CN | disclosed |
| WO-2022170198-A1 | UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF | FAXIAN THERAPEUTICS, LLC (US) | 2022-08-11 | — | — | WO | disclosed |
| CN-114867727-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111349119-B | Pterene pyridazine octadentate double platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-114671813-A | Photosensitizer with activities of fluorescence imaging and photodynamic killing of gram-positive bacteria and preparation method and application thereof | 内蒙古大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-114591300-A | Heterocyclic compounds as THR beta agonists and uses thereof | 南京圣和药业股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112469721-B | Triazolopyrimidine compounds and their use for the treatment of cancer | 迪哲(江苏)医药股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-110520416-B | Polysubstituted pyridone derivative, preparation method and medical application thereof | 北京越之康泰生物医药科技有限公司 | 2022-06-03 | — | — | CN | disclosed |
| CN-112004845-B | Resin composition, laminate, semiconductor wafer with resin composition layer, substrate, and semiconductor device | 三菱瓦斯化学株式会社 | 2022-05-31 | — | — | CN | disclosed |
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114555592-A | 2-azaspiro [3.4] octane derivatives as M4 agonists | 诺华股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114524819-A | Pesticidally active polycyclic derivatives with sulfur-containing substituents | 先正达参股股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-114516840-A | Preparation method of 2- [ (6-chloropyridazin-3-yl) thio ] -N, N-diethylacetamide | 安徽修一制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516840-A | Preparation method of 2- [ (6-chloropyridazin-3-yl) thio ] -N, N-diethylacetamide | 安徽修一制药有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-113582974-B | Compound as protein degradation agent and preparation method and medical application thereof | 江西济民可信集团有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114478478-A | N- (1- (6- (substituted phenyl) pyridazine-3-yl) piperidine-3-yl) amine/amide derivative and preparation method thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478361-A | Method for preparing nitrogen heterocyclic aromatic hydrocarbon compound by coupling reaction without metal catalysis | 浙江工业大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-110036012-B | Pyrido [3,4-d ] pyrimidine derivatives and pharmaceutically acceptable salts thereof | 帝人制药株式会社 | 2022-05-10 | — | — | CN | disclosed |
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437039-A | CD73 inhibitor and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-05-06 | — | — | CN | disclosed |
| CN-114437038-A | Pyridazine alkyne compound and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |
| CN-107108632-B | Deuterated triazolopyridazines as kinase modulators | 詹森药业股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-110041316-B | TAM family kinase/CSF 1R kinase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-114315839-A | Pyrimidinedione compounds and use thereof | 武汉人福创新药物研发中心有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114276331-A | 4-aminopiperidine compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2022-04-05 | — | — | CN | disclosed |
| CN-112409340-B | Halogen substituted phenyl ether compound and application thereof | 海创药业股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-3965884-A1 | MODULATORS OF THR-BETA AND METHODS OF USE THEREOF | Aligos Therapeutics, Inc. (US) | 2022-03-16 | — | — | EP | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| WO-2022041026-A1 | PYRIDAZINONE COMPOUNDS | InventisBio Co., Ltd. (CN) | 2022-03-03 | — | — | WO | disclosed |
| WO-2022042691-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-03 | — | — | WO | disclosed |
| CN-112645936-B | Substituted pyridazinone compound and use thereof | 山东第一医科大学(山东省医学科学院) | 2022-03-01 | — | — | CN | disclosed |
| CN-111093975-B | Laminate for high-frequency circuit, method for producing same, use thereof, and B-stage | JSR株式会社 | 2022-03-01 | — | — | CN | disclosed |
| CN-114105884-A | Preparation method and crystal form of PDE4 inhibitor clobiplane | 兰晟生物医药(苏州)有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114126613-A | Methods and compositions for modulating splicing | 斯基霍克疗法公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114072396-A | Quinoline and cinnoline derivatives as DNA-PK inhibitors | 南京明德新药研发有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-114072390-A | RAD51 inhibitors | 赛泰尔治疗公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-108349966-B | 1,3, 4-thiadiazole compounds and their use in the treatment of cancer | 阿斯利康(瑞典)有限公司 | 2022-02-15 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |
| CN-110862350-B | Pterene pyridazine tetradentate platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-110862350-B | Pterene pyridazine tetradentate platinum complex phosphorescent material and preparation method and application thereof | 南京邮电大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-114008025-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-02-01 | — | — | CN | disclosed |