SCHEMBL38738

SCHEMBL38738

Nc1ccc(Cl)nn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29708474 1.00
Bicarbonate SCHEMBL746393 0.88 ALDH1A1 (0.40)
SCHEMBL31490392 0.80
SCHEMBL111337 0.80
SCHEMBL29367162 0.80
SCHEMBL1255843 0.80
Trifluoroacetic Acid SCHEMBL4114425 0.79 JUN (0.39)
SCHEMBL14844352 0.79 LMNA (0.41)
Ammonia Solution, Strong SCHEMBL25301697 0.77
SCHEMBL16305172 0.77 ALDH1A1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3072 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119495755-A Catalyst, preparation method thereof, membrane electrode and fuel cell 一汽解放汽车有限公司 2025-02-21 CN claimed
CN-114755320-B Detection method of 3-amino-6-methoxypyridazine related substances 南京方生和医药科技有限公司 2024-10-01 CN claimed
WO-2024069492-A1 PROCESSES FOR THE PREPARATION AND MANUFACTURE OF RELUGOLIX MACFARLAN SMITH LIMITED (GB) 2024-04-04 WO claimed
CN-117756729-A Preparation method of deuterium-celecoxib and intermediate thereof 上海鼎雅药物化学科技有限公司 2024-03-26 CN claimed
CN-117417340-A Preparation method of 6-chloroimidazo [1,2-b ] pyridazine-3-carbonitrile 山东省科学院菏泽分院 2024-01-19 CN claimed
CN-117174924-A Non-noble metal catalyst, preparation method thereof, fuel cell and automobile 一汽解放汽车有限公司 2023-12-05 CN claimed
CN-114573563-A Bifunctional molecular compound for inducing PD-L1 protein degradation and preparation and application thereof 沈阳药科大学 2022-06-03 CN claimed
CN-112321592-B Synthesis method of 6-chloroimidazo [1,2-b ] pyridazine-3-carbonitrile 山东省科学院菏泽分院 2022-03-04 CN claimed
CN-112321592-A Synthesis method of 6-chloroimidazo [1,2-b ] pyridazine-3-carbonitrile 山东省科学院菏泽分院 2021-02-05 CN claimed
CN-108059206-A For three area's adsorptive reactors of orthophosphates in Adsorption waste water 北京益清源环保科技有限公司 2018-05-22 CN claimed
WO-2006086445-A2 COMBINATION THERAPY XENON PHARMACEUTICALS INC. (CA) 2006-08-17 WO claimed
EP-1654260-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS Pfizer Products Inc. (US) 2006-05-10 EP claimed
EP-1648874-A2 PIPERAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2006-04-26 EP claimed
US-20050107381-A1 6-membered heteroaryl compounds for the treatment of neurodegenerative disorders PFIZER, INC. 2005-05-19 US claimed
US-20050065143-A1 Pyridazine derivatives and their use as therapeutic agents XENON PHARMACEUTICALS INC. (CA) 2005-03-24 US claimed
WO-2005011601-A2 6-MENBERED HETEROARYL COMPOUNDS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS PFIZER PRODUCTS, INC. (US) 2005-02-10 WO claimed
WO-2005011655-A2 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2005-02-10 WO claimed
US-20040110778-A1 Heterocyclic compounds as ligands of the GABAA receptor YOHANNES DANIEL (US) 2004-06-10 US claimed
US-20030105081-A1 Heterocyclic compounds as ligands of the GABAA receptor PFIZER INC 2003-06-05 US claimed
US-4287194-A Compositions with potentiated hypotensive effects RICHTER GEDEON VEGYESZETI GYAR RT. (HU) 1981-09-01 US claimed