Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | MMP13 | P45452 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476144 | 0.84 | MMP13 (0.60) | HTTMMP13KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL16598258 | 0.83 | HTT (0.76) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL29800992 | 0.82 | HTT (1.00) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL18416069 | 0.79 | MMP13 (1.00) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL5209577 | 0.78 | MMP13 (0.73) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL13728048 | 0.78 | MMP13 (0.77) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL29505822 | 0.76 | SLC40A1 (0.48) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL4174785 | 0.76 | SMN1; SMN2 (0.59) | HTTPOLBKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL23063797 | 0.76 | HTT (0.69) | HTTMMP13POLBTSHRKMT2A | |
| SCHEMBL5095582 | 0.76 | POLB (0.67) | HTTMMP13POLBTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112675170-B | Application of V027-0576 in preparation of antitumor drugs | 南华大学附属第一医院 | 2022-02-01 | — | — | CN | disclosed |