Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 8/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22712556 | 1.00 | DGAT1 (0.59) | DGAT1FFAR1LPLLIPGAAK1 | |
| SCHEMBL22086013 | 0.89 | DGAT1 (0.60) | DGAT1FFAR1LPLLIPGAAK1 | |
| SCHEMBL4046507 | 0.89 | DGAT1 (0.57) | DGAT1FFAR1LPLLIPGAAK1 | |
| SCHEMBL16787846 | 0.86 | DGAT1 (0.69) | DGAT1FFAR1LPLLIPGAAK1 | |
| SCHEMBL2066133 | 0.84 | DGAT1 (0.56) | DGAT1FFAR1LPLLIPGCA1 | |
| SCHEMBL25475421 | 0.83 | DGAT1 (0.55) | DGAT1FFAR1LPLLIPGAAK1 | |
| SCHEMBL1284745 | 0.83 | DGAT1 (0.58) | DGAT1FFAR1LPLLIPGCA1 | |
| SCHEMBL1284321 | 0.83 | DGAT1 (0.55) | DGAT1FFAR1LPLLIPGCA1 | |
| SCHEMBL10224532 | 0.83 | DGAT1 (0.55) | DGAT1LPLLIPGCA1CA2 | |
| SCHEMBL29631065 | 0.83 | DGAT1 (0.58) | DGAT1FFAR1LPLLIPGUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3968983-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | F. Hoffmann-La Roche AG (CH) | 2022-03-23 | — | — | EP | disclosed |
| CN-114007605-A | Macrocyclic broad spectrum antibiotics | 豪夫迈·罗氏有限公司 | 2022-02-01 | — | — | CN | disclosed |