Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | PTPRA | P18433 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18341946 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2AKR1B1KDM6BPTPRAHSPA5 | |
| SCHEMBL16815384 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2AKR1B1KDM6BPTPRAHSPA5 | |
| SCHEMBL352381 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2AKR1B1KDM6BPTPRAHSPA5 | |
| SCHEMBL8319229 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2AKR1B1KDM6BPTPRAHSPA5 | |
| SCHEMBL7559115 | 0.88 | KDM6B (0.53) | SMN1; SMN2AKR1B1KDM6BPTPRACYP1A2 | |
| SCHEMBL6535663 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2AKR1B1KDM6BPTPRAKMT2A | |
| SCHEMBL490938 | 0.83 | KMT2A (0.60) | SMN1; SMN2AKR1B1HSPA5KMT2AHIF1A | |
| SCHEMBL29008432 | 0.82 | AKR1B1 (0.48) | SMN1; SMN2AKR1B1HSPA5HIF1ACYP2D6 | |
| SCHEMBL7388453 | 0.82 | AKR1B1 (0.57) | AKR1B1HSPA5KMT2AHIF1ACYP2D6 | |
| SCHEMBL8228835 | 0.81 | AKR1B1 (0.52) | SMN1; SMN2AKR1B1KDM6BHSPA5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346810-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | Unigen, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115698002-A | Compositions and methods for parasite control | 菲利普莫里斯生产公司 | 2023-02-03 | — | — | CN | disclosed |
| WO-2022256624-A1 | COMPOSITIONS FOR REGULATING HOMEOSTASIS OF CORTISOL AND IMPROVING SLEEP QUALITY AND METHODS OF USE AND PRODUCTION THEREOF | UNIGEN, INC. (US) | 2022-12-08 | — | — | WO | disclosed |
| CN-110719779-B | Synergistic composition comprising non-racemic proportions of (R) -dimiracetam (1) and (S) -dimiracetam (2) | 美蒂斯制药公司 | 2022-02-01 | — | — | CN | disclosed |