SCHEMBL7559115

SCHEMBL7559115

O=C(O)C(O)Cc1ccc(O)cc1.O=C(O)C(O)Cc1ccccc1O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.53
KEAP1 Q14145 1/20 0.50
SLC6A2 P23975 1/20 0.48
SLC7A5 Q01650 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TRPV1 Q8NER1 1/20 0.44
AKR1B1 P15121 1/20 0.44
POLB P06746 1/20 0.44
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
MME P08473 2/20 0.41
CYP1A2 P05177 1/20 0.41
PTPRA P18433 1/20 0.41
ANPEP P15144 2/20 0.40
ERAP2 Q6P179 2/20 0.40
ERAP1 Q9NZ08 2/20 0.40
ACE P12821 1/20 0.40
LAP3 P28838 1/20 0.40
ENPEP Q07075 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352381 0.88 SMN1; SMN2 (0.56) KDM6BSLC6A2SLC7A5SMN1; SMN2AKR1B1
SCHEMBL29367333 0.88 SMN1; SMN2 (0.56) KDM6BSLC6A2SLC7A5SMN1; SMN2AKR1B1
SCHEMBL18341946 0.88 SMN1; SMN2 (0.56) KDM6BSLC6A2SLC7A5SMN1; SMN2AKR1B1
SCHEMBL16815384 0.88 SMN1; SMN2 (0.56) KDM6BSLC6A2SLC7A5SMN1; SMN2AKR1B1
SCHEMBL8319229 0.88 SMN1; SMN2 (0.56) KDM6BSLC6A2SLC7A5SMN1; SMN2AKR1B1
SCHEMBL235131 0.85 KDM6B (0.63) KDM6BSLC6A2SLC7A5TRPV1POLB
SCHEMBL1067448 0.85 KDM6B (0.63) KDM6BSLC6A2SLC7A5TRPV1POLB
SCHEMBL289562 0.85 KDM6B (0.63) KDM6BSLC6A2SLC7A5TRPV1POLB
SCHEMBL8323543 0.85 KDM6B (0.63) KDM6BSLC6A2SLC7A5TRPV1POLB
Water SCHEMBL4812235 0.83 KDM6B (0.61) KDM6BSLC6A2SLC7A5TRPV1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413528-B1 Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use YU RUEY J (US) 1995-11-15 EP claimed
WO-2002067890-A2 METHOD AND PRODUCT FOR SKIN LIGHTENING UNILEVER PLC (GB) 2002-09-06 WO disclosed