Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 3/20 | 0.37 |
| ▸ | TGM1 | P22735 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28997043 | 0.91 | TGM2 (0.50) | TGM2MTNR1ANPC1RAB9AGSTO1 | |
| SCHEMBL28997004 | 0.90 | TGM2 (0.41) | TGM2BTKNPC1RAB9AEGFR | |
| SCHEMBL29366852 | 0.90 | TGM2 (0.41) | TGM2BTKNPC1RAB9AEGFR | |
| SCHEMBL29369906 | 0.87 | TGM2 (0.42) | TGM2MTNR1ABTKF13A1TGM1 | |
| SCHEMBL28996985 | 0.86 | TGM2 (0.50) | TGM2MTNR1ABTKEGFR | |
| SCHEMBL28996940 | 0.84 | TGM2 (0.44) | TGM2MTNR1ANPC1RAB9AGSTO1 | |
| SCHEMBL28997537 | 0.84 | TGM2 (0.53) | TGM2BRAFKDR | |
| SCHEMBL28996914 | 0.84 | TGM2 (0.53) | TGM2BRAFKDR | |
| SCHEMBL28997076 | 0.84 | BRD4 (0.46) | TGM2NPC1RAB9ABRD4EGFR | |
| SCHEMBL26124319 | 0.84 | TGM2 (0.53) | TGM2BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |