SCHEMBL29369327

SCHEMBL29369327

CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1146577 1.00 TLR7 (1.00) TLR7
SCHEMBL1146061 0.97 TLR7 (1.00) TLR7
SCHEMBL1146374 0.96 TLR7 (1.00) TLR7
SCHEMBL26347160 0.91 TLR7 (0.84) TLR7
SCHEMBL1145701 0.86 TLR7 (0.79) TLR7
SCHEMBL1145698 0.85 TLR7 (1.00) TLR7
SCHEMBL1146490 0.85 TLR7 (1.00) TLR7
SCHEMBL1146261 0.85 TLR7 (0.73) TLR7
SCHEMBL20756317 0.84 TLR7 (0.73) TLR7
SCHEMBL17417198 0.84 TLR7 (1.00) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 512 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665402-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS Danmarks Tekniske Universitet (DK) 2025-12-24 — — EP claimed
US-20250270316-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF TIANJIN LIPOGEN TECH CO LTD (CN) 2025-08-28 — — US claimed
WO-2025010407-A2 NANOSCALE METAL-ORGANIC FRAMEWORKS WITH X-RAY TRIGGERABLE PRODRUGS FOR COMBINATION RADIOTHERAPY, CHEMOTHERAPY, AND IMMUNOTHERAPY THE UNIVERSITY OF CHICAGO (US) 2025-01-09 — — WO claimed
WO-2024170742-A1 COPOLYMER-DRUG CONJUGATE FOR TREATMENT OF TUMOURS DANMARKS TEKNISKE UNIVERSITET (DK) 2024-08-22 — — WO claimed
CN-117881419-A Pharmaceutical combination and use thereof 天津立博美华基因科技有限责任公司 2024-04-12 — — CN claimed
US-11773098-B2 Solid forms of a toll-like receptor modulator GILEAD SCIENCES, INC. (US) 2023-10-03 — — US claimed
WO-2023274275-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF 天津立博美华基因科技有限责任公司 2023-01-05 — — WO claimed
CN-122055369-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
CN-122055373-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 — — CN disclosed
CN-122036801-A Crystalline forms of tenofovir alafenamide 吉利德科学公司 2026-05-15 — — CN disclosed
US-20260130893-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-05-14 — — US disclosed
CN-122005785-A Method for identifying HIV patients susceptible to therapy with GP 120V 3 glycan-directed antibodies 吉利德科学公司 2026-05-12 — — CN disclosed
EP-4735445-A1 KRAS MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-05-06 — — EP disclosed
EP-3972645-A1 METHODS OF IDENTIFYING HIV PATIENTS SENSITIVE TO THERAPY WITH GP120 V3 GLYCAN-DIRECTED ANTIBODIES Gilead Sciences, Inc. (US) 2022-03-30 — — EP disclosed
CN-114245807-A FLT3L-FC fusion proteins and methods of use 吉利德科学公司 2022-03-25 — — CN disclosed
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS GILEAD SCIENCES, INC. 2022-03-10 — — US disclosed
WO-2022046644-A1 MULTI-SPECIFIC ANTIGEN BINDING MOLECULES TARGETING HIV AND METHODS OF USE GILEAD SCIENCES, INC. (US) 2022-03-03 — — WO disclosed
WO-2022040596-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2022-02-24 — — WO disclosed
US-20220049021-A1 FLT3L-Fc FUSION PROTEINS AND METHODS OF USE GILEAD SCIENCES, INC. 2022-02-17 — — US disclosed
US-11236085-B2 PD-1/PD-L1 inhibitors GILEAD SCIENCES, INC. (US) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220073473-A1 TOLL LIKE RECEPTOR MODULATOR COMPOUNDS TLR8, TLR3, TLR6 TLR7 9/4885
US-20260130893-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT5, PRMT1, PRMT6 TLR7 4000/4885
US-11773098-B2 Solid forms of a toll-like receptor modulator TLR4, TLR3, TLR6 TLR7 6/4885
US-11236085-B2 PD-1/PD-L1 inhibitors PDCD1, CD274, PDCD1LG2 TLR7 2180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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