SCHEMBL29369397

SCHEMBL29369397

Cn1cc(C(=O)Nc2ccccc2-c2ccccc2C(F)(F)F)c(C(F)(F)F)n1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
POLB P06746 2/20 0.56
ATM Q13315 1/20 0.46
NTRK1 P04629 4/20 0.45
NR3C1 P04150 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
STING1 Q86WV6 1/20 0.43
EPHB3 P54753 1/20 0.43
GAA P10253 1/20 0.43
IRAK4 Q9NWZ3 2/20 0.42
KMT2A Q03164 2/20 0.42
NPC1 O15118 1/20 0.42
TSHR P16473 1/20 0.42
RAB9A P51151 1/20 0.42
MEN1 O00255 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL122740 1.00 LMNA (0.56) LMNAPOLBATMNTRK1NR3C1
SCHEMBL21063361 0.91 LMNA (0.52) LMNAPOLBATMNTRK1NR3C1
SCHEMBL303186 0.88 LMNA (0.56) LMNAPOLBATMNTRK1STING1
SCHEMBL13936356 0.88 LMNA (0.56) LMNAPOLBATMNTRK1STING1
SCHEMBL1240819 0.88 POLB (0.42) LMNAPOLBNR3C1SMN1; SMN2EPHB3
SCHEMBL27737488 0.87 POLB (0.55) LMNAPOLBATMNTRK1NR3C1
SCHEMBL302989 0.87 POLB (0.61) LMNAPOLBATMNTRK1NR3C1
SCHEMBL1085471 0.87 LMNA (0.57) LMNAPOLBATMNTRK1IRAK4
SCHEMBL4100577 0.86 LMNA (0.54) LMNAPOLBATMNTRK1NR3C1
SCHEMBL28790893 0.86 ATM (0.47) LMNAPOLBATMNTRK1NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384016-A1 ACTIVE COMPOUND COMBINATIONS AND FUNGICIDE COMPOSITIONS COMPRISING THOSE Bayer Aktiengesellschaft (DE) 2024-06-19 EP claimed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 CN claimed
EP-4262394-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS Bayer Aktiengesellschaft (DE) 2023-10-25 EP claimed
EP-4250926-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI Industries Ltd. (IN) 2023-10-04 EP claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
EP-4175476-A1 A PESTICIDALLY ACTIVE MIXTURE COMPRISING THIETANYLOXY COMPOUND, OXIDES OR SALTS THEREOF PI Industries Ltd. (IN) 2023-05-10 EP claimed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
EP-4167740-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-26 EP claimed
CN-115955916-A Active compound combinations 拜耳公司 2023-04-11 CN claimed
EP-4156936-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-05 EP claimed
CN-115551352-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN claimed
CN-115551354-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN claimed
CN-115551355-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-30 CN claimed
CN-115515426-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2022-12-23 CN claimed
WO-2022243810-A1 NOVEL AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-11-24 WO claimed
EP-4037485-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING FATTY ACIDS Bayer Aktiengesellschaft (DE) 2022-08-10 EP claimed
CN-114760842-A Active substance combinations comprising fatty acids 拜耳公司 2022-07-15 CN claimed
WO-2022130188-A1 AGROCHEMICAL COMPOSITION COMPRISING PIPERIDINE THIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2022-06-23 WO claimed
WO-2022129200-A1 USE OF DHODH INHIBITOR FOR CONTROLLING RESISTANT PHYTOPATHOGENIC FUNGI IN CROPS BAYER AKTIENGESELLSCHAFT (DE) 2022-06-23 WO claimed
WO-2022113033-A1 AGROCHEMICAL COMPOSITION COMPRISING 3-SUBSTITUTED PHENYLAMIDINE COMPOUNDS AND USE THEREOF PI INDUSTRIES LTD. (IN) 2022-06-02 WO claimed