Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26332449 | 1.00 | POLB (0.42) | POLBRAB9ADCUN1D1TP53SMN1; SMN2 | |
| SCHEMBL28996931 | 0.90 | TRPV1 (0.41) | EGFRTRPV1 | |
| SCHEMBL29366854 | 0.90 | TRPV1 (0.41) | EGFRTRPV1 | |
| SCHEMBL26332480 | 0.82 | DCUN1D1 (0.41) | POLBRAB9ADCUN1D1TP53SMN1; SMN2 | |
| SCHEMBL29366839 | 0.82 | DCUN1D1 (0.41) | POLBRAB9ADCUN1D1TP53SMN1; SMN2 | |
| SCHEMBL30356990 | 0.80 | EGFR (0.49) | POLBRAB9ADCUN1D1SMN1; SMN2EGFR | |
| SCHEMBL30357001 | 0.80 | EGFR (0.49) | POLBRAB9ADCUN1D1SMN1; SMN2EGFR | |
| SCHEMBL28996911 | 0.80 | EGFR (0.49) | POLBRAB9ADCUN1D1SMN1; SMN2EGFR | |
| SCHEMBL28996943 | 0.80 | EGFR (0.49) | POLBRAB9ADCUN1D1SMN1; SMN2EGFR | |
| SCHEMBL29369433 | 0.80 | EGFR (0.49) | POLBRAB9ADCUN1D1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | disclosed |
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |