Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366854 | 1.00 | TRPV1 (0.41) | TRPV1TGM2PDE2ATEAD1CCR2 | |
| SCHEMBL26332449 | 0.90 | POLB (0.42) | TRPV1EGFR | |
| SCHEMBL29369435 | 0.90 | POLB (0.42) | TRPV1EGFR | |
| SCHEMBL25414485 | 0.80 | TGM2 (0.56) | TRPV1TGM2TEAD1EGFR | |
| SCHEMBL28997013 | 0.80 | TGM2 (0.56) | TRPV1TGM2TEAD1EGFR | |
| SCHEMBL28996924 | 0.80 | TGM2 (0.56) | TRPV1TGM2TEAD1EGFR | |
| SCHEMBL28996908 | 0.80 | FFAR1 (0.49) | TEAD1 | |
| SCHEMBL29369830 | 0.80 | FFAR1 (0.49) | TEAD1 | |
| SCHEMBL28997016 | 0.74 | FFAR1 (0.44) | EGFR | |
| SCHEMBL29369580 | 0.74 | FFAR1 (0.44) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |