Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 16/20 | 0.52 |
| ▸ | BMPR1A | P36894 | 16/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 16/20 | 0.52 |
| ▸ | ACVRL1 | P37023 | 16/20 | 0.52 |
| ▸ | ACVR1 | Q04771 | 16/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995177 | 1.00 | BMPR1B (0.52) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995174 | 1.00 | BMPR1B (0.52) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995250 | 0.83 | BMPR1B (0.54) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995251 | 0.83 | BMPR1B (0.54) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29370644 | 0.83 | BMPR1B (0.60) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995274 | 0.83 | BMPR1B (0.60) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20995275 | 0.83 | BMPR1B (0.60) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29042024 | 0.82 | PIK3C3 (0.54) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL29373224 | 0.78 | HSD11B1 (0.49) | BMPR1BBMPR1ATGFBR1ACVRL1ACVR1 | |
| SCHEMBL20240880 | 0.72 | HPGD (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014844-B | Aminopyridine derivatives and their use as selective ALK-2 inhibitors | 诺华股份有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-114014844-A | Aminopyridine derivatives and their use as selective ALK-2 inhibitors | 诺华股份有限公司 | 2022-02-08 | — | — | CN | disclosed |