Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 8/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30303760 | 1.00 | CES1 (0.71) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL29408351 | 0.84 | CES1 (0.90) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL44496 | 0.84 | CES1 (0.90) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL13712393 | 0.84 | CES1 (1.00) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL29437756 | 0.84 | CES1 (0.90) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL66102 | 0.81 | CES1 (0.54) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL29370260 | 0.81 | CES1 (0.54) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL676830 | 0.80 | MAOA (0.67) | CES1MAOAMAOBBCHEMIF | |
| SCHEMBL11327557 | 0.77 | CES1 (0.50) | CES1MAOAL3MBTL1TDP1MAOB | |
| SCHEMBL2231281 | 0.77 | CES1 (0.77) | CES1MAOAL3MBTL1TDP1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105884600-B | 1- tetralone loop coils diene, its synthetic method and its application | 安阳工学院 | 2018-07-27 | — | — | CN | claimed |
| CN-105884600-A | 1-tetralone spiro-diene as well as synthetic method and application thereof | 安阳工学院 | 2016-08-24 | — | — | CN | claimed |
| EP-0558069-B1 | Process for producing 2-methyl-1-naphthol | KURARAY CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5278343-A | Process for producing 2-methyl-1-naphthol | KURARAY COMPANY, LTD. (JP) | 1994-01-11 | — | — | US | claimed |
| EP-0558069-A1 | Process for producing 2-methyl-1-naphthol | KURARAY CO., LTD. (JP) | 1993-09-01 | — | — | EP | claimed |
| US-4745222-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-17 | — | — | US | claimed |
| JP-6009467-A | — | — | None | — | — | JP | disclosed |
| EP-3855519-A2 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3855519-A2 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2021-07-28 | — | — | EP | disclosed |
| EP-3428986-B1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORP (US) | 2021-01-20 | — | — | EP | disclosed |
| EP-2691372-B1 | TOTAL SYNTHESIS OF REDOX-ACTIVE 1.4-NAPHTHOQUINONES AND THEIR METABOLITES AND THEIR THERAPEUTIC USE AS ANTIMALARIAL AND SCHISTOMICIDAL AGENTS | CENTRE NAT RECH SCIENT (FR) | 2019-10-16 | — | — | EP | disclosed |
| EP-3428986-A1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-3428986-A1 | STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS | Universal Display Corporation (US) | 2019-01-16 | — | — | EP | disclosed |
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0409530-A1 | Catalytic preparation of optically active ketones | Takasago International Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |
| EP-0127143-B1 | NOVEL ARYLOXYCYCLOALKANOLAMINOALKYLENE ARYL KETONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4868315-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4745222-A | HYPOTENSIVE AGENTS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0127143-A2 | Novel aryloxycycloalkanolaminoalkylene aryl ketones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-12-05 | — | — | EP | disclosed |
| US-4016281-A | Tetralone and indanone compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-04-05 | — | — | US | disclosed |