Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 11/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 7/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551781 | 1.00 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2728205 | 1.00 | PNMT (0.57) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL8716290 | 0.88 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL30942655 | 0.88 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL6575309 | 0.88 | PNMT (0.50) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL5620372 | 0.83 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL22271652 | 0.83 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL1948741 | 0.83 | PNMT (0.55) | PNMTADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL7515399 | 0.83 | PNMT (0.56) | PNMTADRA2AADRA2BADRA2C | |
| SCHEMBL2246074 | 0.82 | PNMT (0.62) | PNMTADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-B | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2024-10-18 | — | — | CN | disclosed |
| EP-4188907-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2023-06-07 | — | — | EP | disclosed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022023460-A1 | ACRYLAMIDE-SUBSTITUTED INDANE COMPOUNDS AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2022-02-03 | — | — | WO | disclosed |