Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104914 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| Thiourea SCHEMBL8854711 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL9616082 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1ATM | |
| SCHEMBL9872833 | 0.79 | ATM (0.44) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL29026131 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AL3MBTL1ATM | |
| SCHEMBL4210973 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| SCHEMBL38002 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AL3MBTL1ATM | |
| Hydrochloric Acid SCHEMBL8764185 | 0.71 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AGAAL3MBTL1 | |
| Methyl Alcohol SCHEMBL27709287 | 0.71 | ATM (0.41) | ALDH1A1MEN1KMT2AL3MBTL1ATM | |
| SCHEMBL3797066 | 0.71 | KMT2A (0.59) | ALDH1A1TP53TYRTSHRTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2105433-B1 | Modular scaffold for the design of specific molecules for the use as peptidomimetics and inhibitors of protein interaction | UNIV DRESDEN TECH (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-2105433-A1 | Modular scaffold for the design of specific molecules for the use as peptidomimetics and inhibitors of protein interaction | Technische Universität Dresden (DE) | 2009-09-30 | — | — | EP | disclosed |