SCHEMBL3797066

SCHEMBL3797066

NC(=S)NN(c1ccccc1)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.59
MEN1 O00255 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 9/20 0.53
NPSR1 Q6W5P4 2/20 0.53
GAA P10253 7/20 0.47
LMNA P02545 3/20 0.47
ALOX12 P18054 2/20 0.47
MAPT P10636 2/20 0.47
HTT P42858 2/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
TP53 P04637 1/20 0.46
TYR P14679 1/20 0.46
TSHR P16473 1/20 0.46
TAS2R38 P59533 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 2/20 0.45
GPR55 Q9Y2T6 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29028454 0.84 KMT2A (0.57) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL9082914 0.80 ALDH1A1 (0.50) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL28420044 0.78 ALDH1A1 (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL27839869 0.78 ALDH1A1 (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL11875734 0.78 ALDH1A1 (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL2152542 0.78 KMT2A (0.66) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL29028452 0.77 KMT2A (0.59) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL2640797 0.77 KMT2A (0.48) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL28602736 0.76 KMT2A (0.47) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1
SCHEMBL28151420 0.76 KMT2A (0.47) KMT2AMEN1SMN1; SMN2ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897720-B2 Method for removing catalyst residues from polymer solution and polymers purified by the method LG CHEM, LTD. (KR) 2011-03-01 US claimed
CN-1970537-B Process for manufacturing diphenylthiocarbazone SHANGHAI SSS REAGENT CO LTD 2010-05-05 CN claimed
US-20100029900-A1 METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD LG CHEM, LTD. (KR) 2010-02-04 US claimed
WO-2008056938-A1 METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD LG CHEM, LTD. (KR) 2008-05-15 WO claimed
CN-1970537-A Process for manufacturing diphenylthiocarbazone SHANGHAI SSS REAGENT CO LTD (CN) 2007-05-30 CN claimed
EP-3508474-B1 NOVEL THERAPEUTIC AGENT FOR DIABETES JAPAN CHEM RES (JP) 2023-05-17 EP disclosed
CN-109336800-B DHNB (dehydroepiandrosterone) condensed phenylthiosemicarbazide compound as well as preparation method and application thereof 江西中医药大学 2022-11-29 CN disclosed
US-10759749-B2 Therapeutic agent for diabetes JCR PHARMACEUTICALS CO., LTD. (JP) 2020-09-01 US disclosed
US-10759749-B2 Therapeutic agent for diabetes JCR PHARMACEUTICALS CO., LTD. (JP) 2020-09-01 US disclosed
EP-3508474-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR Pharmaceuticals Co., Ltd. (JP) 2019-07-10 EP disclosed
EP-3508474-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR Pharmaceuticals Co., Ltd. (JP) 2019-07-10 EP disclosed
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR PHARMACEUTICALS CO., LTD. (JP) 2019-07-04 US disclosed
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCR PHARMACEUTICALS CO., LTD. (JP) 2019-07-04 US disclosed
WO-2018043399-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES JCRファーマ株式会社 2018-03-08 WO disclosed
EP-1686167-B1 LUBRICATING OIL ADDITIVE AND LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2016-05-25 EP disclosed
US-7897720-B2 Method for removing catalyst residues from polymer solution and polymers purified by the method LG CHEM, LTD. (KR) 2011-03-01 US disclosed
CN-1970537-B Process for manufacturing diphenylthiocarbazone SHANGHAI SSS REAGENT CO LTD 2010-05-05 CN disclosed
US-20100029900-A1 METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD LG CHEM, LTD. (KR) 2010-02-04 US disclosed
WO-2008056938-A1 METHOD FOR REMOVING CATALYST RESIDUES FROM POLYMER SOLUTION AND POLYMERS PURIFIED BY THE METHOD LG CHEM, LTD. (KR) 2008-05-15 WO disclosed
CN-1970537-A Process for manufacturing diphenylthiocarbazone SHANGHAI SSS REAGENT CO LTD (CN) 2007-05-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190202781-A1 NOVEL THERAPEUTIC AGENT FOR DIABETES GPR119, IAPP, DPP4 KMT2A 3897/4885MEN1 4253/4885SMN1; SMN2 3948/4885
US-10759749-B2 Therapeutic agent for diabetes GPR119, IAPP, DPP4 KMT2A 3159/4885MEN1 3662/4885SMN1; SMN2 3104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.