SCHEMBL29370319

SCHEMBL29370319

NC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.58
▸ TP53 P04637 3/20 0.58
▸ CASP3 P42574 3/20 0.55
▸ KMT2A Q03164 2/20 0.53
▸ SLC17A5 Q9NRA2 1/20 0.51
▸ MDM2 Q00987 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119442 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29908070 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL2309917 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL119451 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29401991 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL30096349 0.92 CASP3 (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29391787 0.91 MDM4 (0.51) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL27142935 0.91 KMT2A (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL27142932 0.91 KMT2A (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL20526769 0.90 MDM4 (0.56) MDM4TP53CASP3KMT2ASLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250282826-A1 PREPARATION METHOD, INTERMEDIATES, AND USE OF CYCLIC PEPTIDE TOXIN ALPHA-AMANITIN AND/OR AMANINAMIDE INNER MONGOLIA UNIVERSITY (CN) 2025-09-11 — — US claimed
US-20250205372-A1 RADIOPHARMACEUTICAL COMPOSITIONS, SYNTHETIC METHODS, AND METHODS OF TREATMENT THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-06-26 — — US claimed
CN-119350469-B Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-05-23 — — CN claimed
CN-118490852-B Intracellular-constructed legumain-responded PET/MR bimodal molecular probe and application thereof 安徽医科大学第一附属医院 2025-05-16 — — CN claimed
CN-118459541-B Preparation method, intermediate and application of cyclopeptide toxin alpha-Amanitin and/or AMANINAMIDE 内蒙古大学 2025-03-28 — — CN claimed
CN-118459547-B Preparation method, intermediate and application of cyclopeptide toxin alpha-Amanitin and/or AMANINAMIDE 内蒙古大学 2025-03-11 — — CN claimed
CN-118459546-B Preparation method, intermediate and application of cyclopeptide toxin alpha-Amanitin and/or AMANINAMIDE 内蒙古大学 2025-02-28 — — CN claimed
CN-119504503-A Method for efficiently preparing Fmoc-Dap-OH 成都市科隆化学品有限公司 2025-02-25 — — CN claimed
CN-119391738-A Method for improving soluble expression of recombinant N-acetylglucosamine transferase IVa 北京柏因生物科技有限公司 2025-02-07 — — CN claimed
CN-119350469-A Method for synthesizing CAGRILINTIDE by large fragment SPPS-LPPS mixing method 杭州诺澳生物医药科技有限公司 2025-01-24 — — CN claimed
CN-115038711-A Synthetic method of atosiban 湖北健翔生物制药有限公司 2022-09-09 — — CN claimed
CN-114948850-A Medicine-carrying oligopeptide and preparation method and application of soluble layered microneedle thereof 中国药科大学 2022-08-30 — — CN claimed
CN-114805525-A Preparation method of conopeptide 深圳市健元医药科技有限公司 2022-07-29 — — CN claimed
WO-2022141615-A1 SYNTHESIS METHOD FOR ATOSIBAN 湖北健翔生物制药有限公司 2022-07-07 — — WO claimed
CN-114685614-A Solid-phase synthesis method of atosiban 湖北健翔生物制药有限公司 2022-07-01 — — CN claimed
CN-114685613-A Preparation method of terlipressin impurity Q 深圳翰宇药业股份有限公司 2022-07-01 — — CN claimed
CN-111534495-B Method for improving soluble expression of recombinant N-acetylglucosamine transferase II 江南大学 2022-06-17 — — CN claimed
CN-112175067-B Preparation method of teduglutide 深圳市星银医药有限公司 2022-04-15 — — CN claimed
CN-114315974-A Synthetic method of procatide 江苏诺泰澳赛诺生物制药股份有限公司 2022-04-12 — — CN claimed
CN-109180803-B Somatostatin and preparation method and pharmaceutical composition thereof 成都天台山制药有限公司 2022-02-08 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250282826-A1 PREPARATION METHOD, INTERMEDIATES, AND USE OF CYCLIC PEPTIDE TOXIN ALPHA-AMANITIN AND/OR AMANINAMIDE VIP, PTMA, MLEC MDM4 4560/4885TP53 2026/4885CASP3 1519/4885
US-20250205372-A1 RADIOPHARMACEUTICAL COMPOSITIONS, SYNTHETIC METHODS, AND METHODS OF TREATMENT QPCT, SSTR5, SSTR4 MDM4 1815/4885TP53 494/4885CASP3 1992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback