SCHEMBL119451

SCHEMBL119451

NC(=O)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.58
▸ TP53 P04637 3/20 0.58
▸ CASP3 P42574 3/20 0.55
▸ KMT2A Q03164 2/20 0.53
▸ SLC17A5 Q9NRA2 1/20 0.51
▸ MDM2 Q00987 5/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL119442 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29908070 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL2309917 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29370319 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29401991 1.00 MDM4 (0.58) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL30096349 0.92 CASP3 (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL29391787 0.91 MDM4 (0.51) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL27142935 0.91 KMT2A (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL27142932 0.91 KMT2A (0.54) MDM4TP53CASP3KMT2ASLC17A5
SCHEMBL20526769 0.90 MDM4 (0.56) MDM4TP53CASP3KMT2ASLC17A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
US-12616676-B2 Preparation method and use of modified hydrophobic excipient ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2026-05-05 — — US disclosed
EP-3988538-B1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO LTD (CN) 2024-08-07 — — EP disclosed
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2024-07-11 — — US disclosed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP disclosed
US-20220111056-A1 DRUG-LOADED EMULSION ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US disclosed
CN-109180533-A A kind of N-9- fluorenylmethyloxycarbonyl-D-ASP -4- tert-butyl ester 四川什邡市三高生化实业有限公司 2019-01-11 — — CN disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 — — US disclosed
US-8895231-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-11-25 — — US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 — — US disclosed
US-20120058428-A1 PATTERNING PROCESS AND RESIST COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-08 — — US disclosed
US-20100210552-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2010-08-19 — — US disclosed
US-20080051326-A1 Antiinfective Lipopeptides CUBIST PHARMACEUTICALS, INC. 2008-02-28 — — US disclosed
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-12-13 — — US disclosed
EP-1814588-A2 ANTIINFECTIVE LIPOPEPTIDES Cubist Pharmaceuticals, Inc. (US) 2007-08-08 — — EP disclosed
WO-2006110185-A2 ANTIINFECTIVE LIPOPEPTIDES CUBIST PHARMACEUTICALS, INC. (US) 2006-10-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616676-B2 Preparation method and use of modified hydrophobic excipient CETP, LIPA, MTTP MDM4 3741/4885TP53 1141/4885CASP3 1489/4885
US-20070287670-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS GLP1R, IAPP, GIPR MDM4 4381/4885TP53 3992/4885CASP3 513/4885
US-20220111056-A1 DRUG-LOADED EMULSION SLC43A1, SLC7A1, CETP MDM4 1435/4885TP53 1426/4885CASP3 2182/4885
US-20100210552-A1 HUMAN GLUCAGON-LIKE PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS GLP1R, IAPP, GIPR MDM4 4381/4885TP53 3992/4885CASP3 513/4885
US-20080051326-A1 Antiinfective Lipopeptides VIP, NGLY1, PREP MDM4 1783/4885TP53 3112/4885CASP3 1022/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 MDM4 884/4885TP53 403/4885CASP3 2158/4885
US-20240226343-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R MDM4 4491/4885TP53 517/4885CASP3 3087/4885
US-20220110909-A1 PREPARATION METHOD AND USE OF MODIFIED HYDROPHOBIC EXCIPIENT ABCG2, CYP51A1, HACD3 MDM4 4044/4885TP53 843/4885CASP3 700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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