SCHEMBL29370338

SCHEMBL29370338

Nc1cccc2c(-c3cccc4c(N)cccc34)cccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.81
CYP3A4 P08684 5/20 0.81
HPGD P15428 3/20 0.81
HSD17B10 Q99714 3/20 0.81
TSHR P16473 3/20 0.81
TDP1 Q9NUW8 3/20 0.81
NR4A2 P43354 1/20 0.59
KEAP1 Q14145 3/20 0.57
NFE2L2 Q16236 2/20 0.54
CRHBP P24387 1/20 0.54
CRHR2 Q13324 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.53
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPT P10636 3/20 0.48
USP2 O75604 3/20 0.48
IDO1 P14902 3/20 0.48
KDM4E B2RXH2 2/20 0.48
PARP1 P09874 2/20 0.48
RECQL P46063 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19859798 1.00 ALDH1A1 (0.81) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL29365003 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL48843 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4HPGDHSD17B10TSHR
Hydrochloric Acid SCHEMBL8641121 0.87 CYP3A4 (0.93) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL335367 0.87 ALDH1A1 (0.93) ALDH1A1CYP3A4HPGDHSD17B10TSHR
Ammonia Solution, Strong SCHEMBL7197839 0.87 ALDH1A1 (0.93) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL16623899 0.85 ALDH1A1 (0.77) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL21854609 0.84 ALDH1A1 (0.87) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL16107418 0.84 ALDH1A1 (0.87) ALDH1A1CYP3A4HPGDHSD17B10TSHR
SCHEMBL14876644 0.84 ALDH1A1 (0.87) ALDH1A1CYP3A4HPGDHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109642968-B Optical compensation film with reverse wavelength dispersion 阿克隆聚合物系统有限公司 2022-02-01 CN claimed
CN-109642968-B Optical compensation film with reverse wavelength dispersion 阿克隆聚合物系统有限公司 2022-02-01 CN disclosed