SCHEMBL29370384

SCHEMBL29370384

[N-]=[N+]=NCc1ccnc(CC(N)C(=O)O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ SLC7A5 Q01650 3/20 0.40
▸ PTGS1 P23219 2/20 0.40
▸ PKM P14618 2/20 0.40
▸ ALPI P09923 1/20 0.40
▸ XIAP P98170 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.38
▸ USP2 O75604 1/20 0.38
▸ EGFR P00533 1/20 0.38
▸ LCK P06239 1/20 0.38
▸ FYN P06241 1/20 0.38
▸ ADORA3 P0DMS8 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ HTR2A P28223 1/20 0.38
▸ PTGS2 P35354 1/20 0.38
▸ RECQL P46063 1/20 0.38
▸ HIF1A Q16665 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ GRIA2 P42262 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469193 1.00 HSD17B10 (0.43) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL20339346 1.00 HSD17B10 (0.43) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL15511517 0.82 SLC7A5 (0.41) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL29373039 0.82 SLC7A5 (0.41) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL15469201 0.82 SLC7A5 (0.41) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL20339996 0.80 CYP1A2 (0.39) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL23069027 0.80 NOS3 (0.55) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL23069024 0.80 NOS3 (0.55) HSD17B10SLC7A5PTGS1PKMALPI
SCHEMBL18995811 0.79 HSD17B10 (0.51) HSD17B10CYP1A2SLC7A5PTGS1PKM
SCHEMBL17814914 0.79 SLC7A5 (0.57) HSD17B10CYP1A2SLC7A5PTGS1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076210-A1 CHLAMYDIA VACCINE COMPOSITIONS VAXCYTE, INC. (US) 2025-04-10 — — WO claimed
US-20240358823-A1 CONJUGATED VACCINE CARRIER PROTEINS VAXCYTE, INC. 2024-10-31 — — US claimed
CN-118662649-A Polypeptide-antigen conjugates with unnatural amino acids VAXCYTE公司 2024-09-20 — — CN claimed
CN-117479961-A Purification method of polysaccharide and polypeptide conjugate thereof VAXCYTE公司 2024-01-30 — — CN claimed
EP-4294452-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF VAXCYTE, INC. (US) 2023-12-27 — — EP claimed
EP-4106807-A1 GROUP A STREP IMMUNOGENIC COMPOSITIONS WITH POLYSACCHARIDE-PROTEIN CONJUGATES VAXCYTE, INC. (US) 2022-12-28 — — EP claimed
CN-115175697-A Group A streptococcus immunogenic compositions with polysaccharide-protein conjugates VAXCYTE公司 2022-10-11 — — CN claimed
WO-2022178015-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF VAXCYTE, INC. (US) 2022-08-25 — — WO claimed
EP-3946443-A1 OPTIMIZED CELL-FREE SYNTHESIS OF INVASION PLASMID ANTIGEN B AND RELATED COMPOSITIONS AND METHODS OF USE VAXCYTE, INC. (US) 2022-02-09 — — EP claimed
CN-114025789-A Optimized cell-free synthesis of invasive plasmid antigen B and related compositions and methods of use VAXCYTE公司 2022-02-08 — — CN claimed
EP-4689127-A1 RF1 KO E. COLI STRAINS Sutro Biopharma, Inc. (US) 2026-02-11 — — EP disclosed
WO-2025090513-A1 SHIGELLA VACCINE COMPOSITIONS VAXCYTE, INC. (US) 2025-05-01 — — WO disclosed
WO-2025076210-A1 CHLAMYDIA VACCINE COMPOSITIONS VAXCYTE, INC. (US) 2025-04-10 — — WO disclosed
US-20240358823-A1 CONJUGATED VACCINE CARRIER PROTEINS VAXCYTE, INC. 2024-10-31 — — US disclosed
US-20240342274-A1 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS VAXCYTE, INC. 2024-10-17 — — US disclosed
CN-115175697-A Group A streptococcus immunogenic compositions with polysaccharide-protein conjugates VAXCYTE公司 2022-10-11 — — CN disclosed
WO-2022178015-A1 PURIFICATION PROCESSES FOR POLYSACCHARIDES AND POLYPEPTIDE CONJUGATES THEREOF VAXCYTE, INC. (US) 2022-08-25 — — WO disclosed
WO-2022040266-A1 CARRIER-PROTEIN POLYSACCHARIDE CONJUGATION METHODS VAXCYTE, INC. (US) 2022-02-24 — — WO disclosed
EP-3946443-A1 OPTIMIZED CELL-FREE SYNTHESIS OF INVASION PLASMID ANTIGEN B AND RELATED COMPOSITIONS AND METHODS OF USE VAXCYTE, INC. (US) 2022-02-09 — — EP disclosed
CN-114025789-A Optimized cell-free synthesis of invasive plasmid antigen B and related compositions and methods of use VAXCYTE公司 2022-02-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342274-A1 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS CD74, DNPEP, NGLY1 HSD17B10 3231/4885CYP1A2 4423/4885SLC7A5 227/4885
US-20240358823-A1 CONJUGATED VACCINE CARRIER PROTEINS CD74, LY96, ASNS HSD17B10 2269/4885CYP1A2 4136/4885SLC7A5 91/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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