SCHEMBL17814914

SCHEMBL17814914

[N-]=[N+]=NCc1ccc(CC(N)C(=O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 0.57
▸ PTGS1 P23219 3/20 0.56
▸ ALPI P09923 1/20 0.56
▸ PKM P14618 1/20 0.56
▸ XIAP P98170 1/20 0.56
▸ TPH1 P17752 3/20 0.53
▸ HIF1A Q16665 5/20 0.50
▸ CYP3A4 P08684 3/20 0.50
▸ ALOX15 P16050 3/20 0.50
▸ ALDH1A1 P00352 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ ABCB11 O95342 1/20 0.50
▸ CHRM2 P08172 1/20 0.50
▸ ADRA2A P08913 1/20 0.50
▸ CHRM1 P11229 1/20 0.50
▸ ACHE P22303 1/20 0.50
▸ OPRM1 P35372 1/20 0.50
▸ DRD3 P35462 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15469220 1.00 SLC7A5 (0.57) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23069024 0.85 NOS3 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL23069027 0.85 NOS3 (0.55) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL22669502 0.84 GRIK1 (0.46) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15511517 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL29373039 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469201 0.82 SLC7A5 (0.41) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469207 0.82 HSD17B10 (0.47) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL20339315 0.82 HSD17B10 (0.47) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL15469227 0.81 HSD17B10 (0.42) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates SUTRO BIOPHARMA, INC. (US) 2026-02-03 — — US claimed
US-12427201-B2 Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates SUTRO BIOPHARMA, INC. (US) 2025-09-30 — — US claimed
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2025-07-24 — — US claimed
EP-4588521-A2 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS VAXCYTE, INC. (US) 2025-07-23 — — EP claimed
US-20250230198-A1 COMPOSITIONS AND METHODS FOR MAKING AND USING PROTEIN NANOWIRES WITH TUNABLE FUNCTIONALITY YALE UNIVERSITY 2025-07-17 — — US claimed
CN-120076831-A Anti-ROR 1 antibodies and antibody conjugates, compositions comprising anti-ROR 1 antibodies or antibody conjugates, and methods of making and using anti-ROR 1 antibodies and antibody conjugates 苏特罗生物制药公司 2025-05-30 — — CN claimed
EP-4547284-A1 ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-ROR1 ANTIBODIES OR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-ROR1 ANTIBODIES AND ANTIBODY CONJUGATES Sutro Biopharma, Inc. (US) 2025-05-07 — — EP claimed
US-20250135025-A1 ANTI-ROR1 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI ROR1 ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-ROR1 ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2025-05-01 — — US claimed
EP-3562503-B1 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS VAXCYTE INC (US) 2025-04-23 — — EP claimed
US-20250122306-A1 ANTI-TISSUE FACTOR ANTIBODIES AND ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-TISSUE FACTOR ANTIBODIES OR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-TISSUE FACTOR ANTIBODIES AND ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2025-04-17 — — US claimed
WO-2018126229-A9 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS SUTROVAX, INC. (US) 2019-07-25 — — WO claimed
US-20190144546-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2019-05-16 — — US claimed
WO-2019055909-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES SUTRO BIOPHARMA, INC. (US) 2019-03-21 — — WO claimed
WO-2019055931-A1 ANTI- FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES SUTRO BIOPHARMA, INC. (US) 2019-03-21 — — WO claimed
US-20190083641-A1 ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2019-03-21 — — US claimed
WO-2019023316-A1 METHODS OF USING ANTI-CD74 ANTIBODIES AND ANTIBODY CONJUGATES IN TREATMENT OF T-CELL LYMPHOMA SUTRO BIOPHARMA, INC. (US) 2019-01-31 — — WO claimed
US-20180333484-A1 Polypeptide-Antigen Conjugates with Non-Natural Amino Acids SUTROVAX, INC. (US) 2018-11-22 — — US claimed
WO-2018126229-A2 POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS SUTROVAX, INC. (US) 2018-07-05 — — WO claimed
EP-3271359-A1 ISOQUINOLIDINOBENZODIAZEPINES Cellerant Therapeutics, Inc. (US) 2018-01-24 — — EP claimed
WO-2016149546-A1 ISOQUINOLIDINOBENZODIAZEPINES CELLERANT THERAPEUTICS, INC. (US) 2016-09-22 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427201-B2 Anti-folate receptor antibody conjugates, compositions comprising anti-folate receptor antibody conjugates, and methods of making and using anti-folate receptor antibody conjugates FOLR1, FOLR2, DHFR SLC7A5 743/4885PTGS1 4083/4885ALPI 2698/4885
US-20180333484-A1 Polypeptide-Antigen Conjugates with Non-Natural Amino Acids CD74, DNPEP, NGLY1 SLC7A5 227/4885PTGS1 3633/4885ALPI 1709/4885
US-12540197-B2 Anti-tissue factor antibodies and antibody conjugates, compositions comprising anti-tissue factor antibodies or antibody conjugates, and methods of making and using anti-tissue factor antibodies and antibody conjugates VSIG8, F13B, HNRNPH3 SLC7A5 1194/4885PTGS1 4003/4885ALPI 2042/4885
US-20190083641-A1 ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES FOLR1, FOLR2, DHFR SLC7A5 743/4885PTGS1 4083/4885ALPI 2698/4885
US-20250135025-A1 ANTI-ROR1 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI ROR1 ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-ROR1 ANTIBODY CONJUGATES ROR1, RORA, RORB SLC7A5 3822/4885PTGS1 4254/4885ALPI 661/4885
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD63, CD99 SLC7A5 2691/4885PTGS1 4826/4885ALPI 1470/4885
US-20250122306-A1 ANTI-TISSUE FACTOR ANTIBODIES AND ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-TISSUE FACTOR ANTIBODIES OR ANTIBODY CONJUGATES, AND METHODS OF MAKING AND USING ANTI-TISSUE FACTOR ANTIBODIES AND ANTIBODY CONJUGATES F3, F13B, SERPINA6 SLC7A5 3468/4885PTGS1 1557/4885ALPI 1651/4885
US-20190144546-A1 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI-CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD99, CD63 SLC7A5 427/4885PTGS1 4801/4885ALPI 3100/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback