SCHEMBL29370686

SCHEMBL29370686

CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)N)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPBWR1 P48145 2/20 0.56
IL23R Q5VWK5 5/20 0.56
RXFP1 Q9HBX9 1/20 0.55
KISS1R Q969F8 9/20 0.54
GRPR P30550 1/20 0.53
OPRD1 P41143 1/20 0.52
PTH1R Q03431 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29396822 0.97 NPBWR1 (0.61) NPBWR1IL23RRXFP1PTH1R
SCHEMBL30874395 0.95 NPBWR1 (0.56) NPBWR1IL23RRXFP1KISS1RGRPR
SCHEMBL30377378 0.95 KISS1R (0.56) NPBWR1IL23RRXFP1KISS1RPTH1R
SCHEMBL15849869 0.94 NPBWR1 (0.55) NPBWR1IL23RRXFP1KISS1RGRPR
SCHEMBL677586 0.94 NPBWR1 (0.56) NPBWR1IL23RRXFP1KISS1ROPRD1
SCHEMBL29375423 0.94 NPBWR1 (0.56) NPBWR1IL23RRXFP1KISS1ROPRD1
SCHEMBL29988116 0.93 NPBWR1 (0.61) NPBWR1IL23RRXFP1PTH1R
SCHEMBL31226860 0.92 NPBWR1 (0.64) NPBWR1IL23RRXFP1
SCHEMBL31294865 0.92 NPBWR1 (0.61) NPBWR1IL23RRXFP1PTH1R
SCHEMBL30598170 0.92 NPBWR1 (0.61) NPBWR1IL23RRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 US claimed
WO-2025093774-A1 GLUCAGON-LIKE PEPTIDE 1 AGONISTS Constructive Biology Limited (GB) 2025-05-08 WO claimed
EP-4345104-B1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-08-28 EP claimed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 WO claimed
EP-4326330-A1 GLUCAGON LIKE PEPTIDE COMPOUNDS Novartis AG (CH) 2024-02-28 EP claimed
WO-2023012709-A1 AN IMPROVED PROCESS FOR FMOC SYNTHESIS OF SEMAGLUTIDE USV PRIVATE LIMITED (IN) 2023-02-09 WO claimed
WO-2022224164-A1 GLUCAGON LIKE PEPTIDE COMPOUNDS NOVARTIS AG (CH) 2022-10-27 WO claimed
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2026-04-16 US disclosed
US-12497644-B2 Subtilisin variants and their use Fresenius Kabi Ipsum S.R.L. (IT) 2025-12-16 US disclosed
EP-4602064-A1 METHOD OF MANUFACTURING A PEPTIDE WITH A LYSINE DERIVATIVE Bachem Holding AG (CH) 2025-08-20 EP disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 US disclosed
CN-118791551-B Liquid phase synthesis method of semaglutin dipeptide fragment 质肽药业(泰州)有限公司 2025-02-18 CN disclosed
CN-119161410-A Synthesis method of semaglutin dipeptide fragment 质肽药业(泰州)有限公司 2024-12-20 CN disclosed
EP-3704143-B1 CHEMO-ENZYMATIC SYNTHESIS OF LIRAGLUTIDE, SEMAGLUTIDE AND GLP-1 FRESENIUS KABI IPSUM S R L (IT) 2023-10-18 EP disclosed
EP-4188355-A2 ANTIVIRAL USE OF LIRAGLUTIDE AND GEFITINIB Delta 4 GmbH (AT) 2023-06-07 EP disclosed
CN-116120426-A Method for purifying liraglutide oxidized impurities 江苏诺泰澳赛诺生物制药股份有限公司 2023-05-16 CN disclosed
WO-2023012829-A1 PROCESS FOR THE PREPARATION OF SEMAGLUTIDE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2023-02-09 WO disclosed
WO-2022224164-A1 GLUCAGON LIKE PEPTIDE COMPOUNDS NOVARTIS AG (CH) 2022-10-27 WO disclosed
EP-4073096-A1 A METHOD OF FORMING A CONJUGATE OF A SULFONAMIDE AND A POLYPEPTIDE SANOFI (FR) 2022-10-19 EP disclosed
WO-2022023533-A2 ANTIVIRAL USE OF LIRAGLUTIDE AND GEFITINIB DELTA 4 GMBH (AT) 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE GLP1R, IAPP, VIP NPBWR1 785/4885IL23R 1461/4885RXFP1 83/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG NPBWR1 188/4885IL23R 3237/4885RXFP1 83/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.