SCHEMBL2937240

SCHEMBL2937240

COC(=O)c1nccnc1N(CS(=O)(=O)Cc1ccccc1SC(F)(F)F)OC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
FFAR4 Q5NUL3 12/20 0.36
FFAR1 O14842 5/20 0.36
NTRK1 P04629 2/20 0.33
MPO P05164 1/20 0.32
RORC P51449 1/20 0.31
PTK2 Q05397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17103732 0.91 FFAR4 (0.39) FFAR4FFAR1NTRK1
SCHEMBL271645 0.82 L3MBTL1 (0.40) L3MBTL1FFAR4FFAR1NTRK1MPO
SCHEMBL270215 0.81 L3MBTL1 (0.37) L3MBTL1FFAR4FFAR1NTRK1MPO
SCHEMBL271426 0.80 FFAR4 (0.36) L3MBTL1FFAR4FFAR1NTRK1RORC
SCHEMBL270673 0.78 L3MBTL1 (0.41) L3MBTL1FFAR4FFAR1NTRK1RORC
SCHEMBL270214 0.77 FFAR4 (0.38) L3MBTL1FFAR4FFAR1NTRK1RORC
SCHEMBL17103731 0.72 FFAR4 (0.39) FFAR4FFAR1NTRK1
SCHEMBL271254 0.67 GRM4 (0.38) L3MBTL1PTK2
SCHEMBL9957557 0.66 GRM4 (0.45) L3MBTL1RORC
SCHEMBL271548 0.65 TRPM8 (0.38) L3MBTL1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100323889-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-12-23 US disclosed
EP-2220056-A1 HERBICIDAL COMPOUNDS Syngenta Limited (GB) 2010-08-25 EP disclosed
WO-2009063180-A1 HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2009-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100323889-A1 HERBICIDAL COMPOUNDS CBR3, DDT, CBR1 L3MBTL1 2902/4885FFAR4 2956/4885FFAR1 1221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.