Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Indapamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 1.00 |
| ▸ | CA2 | P00918 | 10/20 | 1.00 |
| ▸ | CA12 | O43570 | 3/20 | 1.00 |
| ▸ | CA3 | P07451 | 3/20 | 1.00 |
| ▸ | CA4 | P22748 | 3/20 | 1.00 |
| ▸ | CA6 | P23280 | 3/20 | 1.00 |
| ▸ | CA5A | P35218 | 3/20 | 1.00 |
| ▸ | CA7 | P43166 | 3/20 | 1.00 |
| ▸ | CA9 | Q16790 | 3/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Indapamide SCHEMBL41303 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL476213 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL2329030 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL29377544 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL163266 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL29496872 | 1.00 | CA1 (1.00) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL2989867 | 0.99 | CA1 (0.98) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL3159715 | 0.99 | CA1 (0.98) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL28261247 | 0.96 | CA1 (0.92) | CA1CA2CA12CA3CA4 | |
| Indapamide SCHEMBL16180488 | 0.94 | CA1 (0.89) | CA1CA2CA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 459 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119740443-B | Deep-shallow part coupling three-dimensional ground stress model parameter optimization method based on data assimilation | 中国海洋大学 | 2025-05-02 | — | — | CN | claimed |
| EP-4544657-A1 | VESSEL POWER SYSTEM COMPRISING GENSETS AND METHOD | DANVEST NETHERLANDS B.V. (NL) | 2025-04-30 | — | — | EP | claimed |
| EP-4544659-A2 | BUILDING POWER SYSTEM AND METHOD | DANVEST NETHERLANDS B.V. (NL) | 2025-04-30 | — | — | EP | claimed |
| CN-119898070-A | Dynamic control system of hydraulic press | 天力重工(如皋)有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119740443-A | Deep-shallow part coupling three-dimensional ground stress model parameter optimization method based on data assimilation | 中国海洋大学 | 2025-04-01 | — | — | CN | claimed |
| WO-2025029139-A1 | DEVICE AND METHOD FOR PORTIONING DOUGH | KAAK GROEP B.V. (NL) | 2025-02-06 | — | — | WO | claimed |
| WO-2025029147-A1 | TOOL, APPARATUS AND METHOD FOR STAMPING DOUGH PORTIONS | SPACE-XYZ IP B.V. (NL) | 2025-02-06 | — | — | WO | claimed |
| WO-2025010072-A1 | METHOD AND SYSTEM FOR TREATING CENTRAL SLEEP APNEA | PERIODIC BREATHING, LLC (US) | 2025-01-09 | — | — | WO | claimed |
| EP-4487407-A1 | SAFETY SYSTEM FOR VEHICLE PROPULSION BATTERY PACK | Iveco S.p.A. (IT) | 2025-01-08 | — | — | EP | claimed |
| EP-4487406-A1 | SAFETY SYSTEM FOR VEHICLE PROPULSION BATTERY PACK | Iveco S.p.A. (IT) | 2025-01-08 | — | — | EP | claimed |
| CN-114923945-A | Method for simulating pore water pressure of tailing filler in high-temperature stope and application of method | 四川大学 | 2022-08-19 | — | — | CN | claimed |
| WO-2022162462-A1 | PROCESS FOR DYEING PRODUCTS OR FABRICS | MAKE IN ITALY SRL (IT) | 2022-08-04 | — | — | WO | claimed |
| WO-2022144731-A1 | METHOD OF JOINING SEGMENTS OF A COMPOSITE COMPONENT | GENERAL ELECTRIC COMPANY (US) | 2022-07-07 | — | — | WO | claimed |
| CN-110189161-B | Block chain consensus method and system for realizing marketing label sharing | 华中科技大学 | 2022-06-17 | — | — | CN | claimed |
| CN-114607478-A | Double-regulation-stage steam turbine unit and operation method | 暨南大学 | 2022-06-10 | — | — | CN | claimed |
| WO-2022117893-A2 | COMBINATION THERAPY FOR PATIENTS HAVING ACUTE AND/OR PERSISTENT DYSPNEA | S-FORM PHARMA (BE) | 2022-06-09 | — | — | WO | claimed |
| WO-2022101328-A1 | STANDALONE HYDRO-DEMETALLIZATION (HDM) UNIT | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2022-05-19 | — | — | WO | claimed |
| WO-2022101329-A1 | INTEGRATED HYDRO-DEMETALLIZATION (HDM) UNIT | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2022-05-19 | — | — | WO | claimed |
| CN-112856526-B | Air volume self-adaptive adjusting method of range hood and range hood | 宁波方太厨具有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-114018700-A | Large-scale soil-rock mixed soil sample indoor compression instrument and filling deformation and stability calculation method | 中国电力工程顾问集团华北电力设计院有限公司 | 2022-02-08 | — | — | CN | claimed |