Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 11/20 | 0.58 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.52 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937304 | 0.84 | RAB9A (0.53) | AVPR2RAB9ANPC1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL5552018 | 0.83 | PDCD1 (0.47) | AVPR2PDCD1CD274RAB9ANPC1 | |
| SCHEMBL1346004 | 0.83 | AVPR2 (0.69) | AVPR2 | |
| Hydrochloric Acid SCHEMBL4195564 | 0.82 | AVPR2 (0.68) | AVPR2 | |
| SCHEMBL2616280 | 0.81 | PDCD1 (0.49) | AVPR2PDCD1CD274RAB9ANPC1 | |
| SCHEMBL2129587 | 0.81 | PDCD1 (0.47) | AVPR2PDCD1CD274RAB9ANPC1 | |
| SCHEMBL2704977 | 0.80 | PDCD1 (0.46) | AVPR2PDCD1CD274RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL2129494 | 0.80 | PDCD1 (0.48) | AVPR2PDCD1CD274RAB9ANPC1 | |
| SCHEMBL6201929 | 0.78 | BRD4 (0.60) | AVPR2PDCD1CD274ALDH1A1 | |
| SCHEMBL8559469 | 0.77 | AVPR2 (0.65) | AVPR2RAB9ANPC1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | claimed |