SCHEMBL29373380

SCHEMBL29373380

N[C@@H](Cc1csc2ccccc12)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.54
DPP4 P27487 2/20 0.53
DPP8 Q6V1X1 2/20 0.53
DPP9 Q86TI2 2/20 0.53
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
MPO P05164 1/20 0.52
TSHR P16473 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
KMT2A Q03164 1/20 0.52
HIF1A Q16665 1/20 0.52
OPRD1 P41143 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1421072 1.00 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9MAPT
SCHEMBL514508 1.00 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9MAPT
SCHEMBL514509 1.00 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9MAPT
SCHEMBL2466886 1.00 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9MAPT
Hydrochloric Acid SCHEMBL31036845 0.98 CYP2A6 (0.53) CYP2A6DPP4DPP8DPP9MAPT
Hydrochloric Acid SCHEMBL4903646 0.98 CYP2A6 (0.53) CYP2A6DPP4DPP8DPP9MAPT
Hydrochloric Acid SCHEMBL4903643 0.98 CYP2A6 (0.53) CYP2A6DPP4DPP8DPP9MAPT
Trifluoroacetic Acid SCHEMBL6161392 0.92 DPP4 (0.48) CYP2A6DPP4DPP8DPP9MAPT
SCHEMBL28905932 0.88 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9OPRD1
SCHEMBL14401103 0.88 CYP2A6 (0.54) CYP2A6DPP4DPP8DPP9OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567639-A Polypeptide conjugates for intracellular delivery of binding peptides 俄亥俄州国家创新基金会 2024-02-20 CN claimed
CN-117529489-A Bicyclic peptide ligands specific for NK cells 拜斯科技术开发有限公司 2024-02-06 CN claimed
EP-4274838-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BicycleTx Limited (GB) 2023-11-15 EP claimed
CN-115135665-A Cyclic proteins comprising cell penetrating peptides 俄亥俄州国家创新基金会 2022-09-30 CN claimed
CN-114805487-A Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2022-07-29 CN claimed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 WO claimed
WO-2022109058-A1 NUCLEASES COMPRISING CELL PENETRATING PEPTIDE SEQUENCES ENTRADA THERAPEUTICS, INC. (US) 2022-05-27 WO claimed
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-09-25 US disclosed
EP-4610269-A1 UROKINASE PLASMINOGEN ACTIVATOR SURFACE RECEPTOR (UPAR) LIGANDS FOR DIAGNOSTIC OR THERAPEUTIC USE 3B Pharmaceuticals GmbH (DE) 2025-09-03 EP disclosed
EP-4608452-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS Eisai R&D Management Co., Ltd. (JP) 2025-09-03 EP disclosed
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof RAYZEBIO, INC. (US) 2025-07-10 US disclosed
WO-2025137441-A1 RADIOPHARMACEUTICALS TARGETING SOMATOSTATIN RECEPTOR 2 AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
WO-2025137443-A1 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING SOMATOSTATIN RECEPTORS AND USES THEREOF RAYZEBIO, INC. (US) 2025-06-26 WO disclosed
WO-2022148974-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NK CELLS BICYCLETX LIMITED (GB) 2022-07-14 WO disclosed
EP-4021473-A1 STAPLED BETA-CATENIN LIGANDS Ohio State Innovation Foundation (US) 2022-07-06 EP disclosed
CN-113912670-B Angiotensin converting enzyme 2 inhibitor, application thereof and anti-coronavirus infection drug 深圳市小分子新药创新中心有限公司 2022-04-08 CN disclosed
EP-3963109-A1 METHODS AND COMPOSITIONS FOR TREATING MELANOMA INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-03-09 EP disclosed
EP-3956446-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF NLRP3 INFLAMMASOME MEDIATED IL-1BETA DEPENDENT DISORDERS INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-02-23 EP disclosed
EP-3952850-A1 USE OF SK2 INHIBITORS IN COMBINATION WITH IMMUNE CHECKPOINT BLOCKADE THERAPY FOR THE TREATMENT OF CANCER Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2022-02-16 EP disclosed
WO-2022023379-A1 METHODS AND COMPOSITIONS FOR PREVENTING AND TREATING A CANCER INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296971-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS GIPR, VIP, GRPR CYP2A6 3815/4885DPP4 1515/4885DPP8 1159/4885
US-20250222146-A1 Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof SSTR2, SSTR4, SSTR5 CYP2A6 3144/4885DPP4 1094/4885DPP8 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.