Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 2/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514508 | 1.00 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9MAPT | |
| SCHEMBL29373380 | 1.00 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9MAPT | |
| SCHEMBL514509 | 1.00 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9MAPT | |
| SCHEMBL2466886 | 1.00 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9MAPT | |
| Hydrochloric Acid SCHEMBL31036845 | 0.98 | CYP2A6 (0.53) | CYP2A6DPP4DPP8DPP9MAPT | |
| Hydrochloric Acid SCHEMBL4903646 | 0.98 | CYP2A6 (0.53) | CYP2A6DPP4DPP8DPP9MAPT | |
| Hydrochloric Acid SCHEMBL4903643 | 0.98 | CYP2A6 (0.53) | CYP2A6DPP4DPP8DPP9MAPT | |
| Trifluoroacetic Acid SCHEMBL6161392 | 0.92 | DPP4 (0.48) | CYP2A6DPP4DPP8DPP9MAPT | |
| SCHEMBL28905932 | 0.88 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9OPRD1 | |
| SCHEMBL14401103 | 0.88 | CYP2A6 (0.54) | CYP2A6DPP4DPP8DPP9OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748183-B1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIV LEIPZIG (DE) | 2018-12-26 | — | — | EP | claimed |
| US-9718861-B2 | Potent ligands of the ghrelin receptor | UNIVERSITAET LEIPZIG (DE) | 2017-08-01 | — | — | US | claimed |
| US-20160022636-A1 | PHYSIOLOGICAL LIGANDS FOR GPR139 | JANSSEN PHARMACEUTICA NV (BE) | 2016-01-28 | — | — | US | claimed |
| EP-2968240-A2 | PHYSIOLOGICAL LIGANDS FOR GPR139 | Janssen Pharmaceutica, N.V. (BE) | 2016-01-20 | — | — | EP | claimed |
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITAET LEIPZIG (DE) | 2015-10-01 | — | — | US | claimed |
| US-20140336216-A1 | PHYSIOLOGICAL LIGANDS FOR GPR139 | JANSSEN PHARMACEUTICA NV (BE) | 2014-11-13 | — | — | US | claimed |
| WO-2014152917-A2 | PHYSIOLOGICAL LIGANDS FOR GPR139 | JANSSEN PHARMACEUTICA NV (BE) | 2014-09-25 | — | — | WO | claimed |
| EP-2748183-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | Universität Leipzig (DE) | 2014-07-02 | — | — | EP | claimed |
| WO-2013026927-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | UNIVERSITÄT LEIPZIG (DE) | 2013-02-28 | — | — | WO | claimed |
| EP-2562181-A1 | Potent ligands of the ghrelin receptor | Universität Leipzig (DE) | 2013-02-27 | — | — | EP | claimed |
| US-20050186289-A1 | Regulation of T cell-mediated immunity by D isomers of inhibitors of indoleamine-2,3-dioxygenase | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2005-08-25 | — | — | US | claimed |
| EP-0699074-B1 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 2002-11-13 | — | — | EP | claimed |
| EP-0699074-A4 | THROMBIN INHIBITORS | MERCK & CO INC (US) | 1998-03-11 | — | — | EP | claimed |
| US-5672582-A | ANTICOAGULANTS; 4-SUBSTITUTED CYCLOHEXYLAMINE DERIVATIVES | MERCK & CO., INC. (US) | 1997-09-30 | — | — | US | claimed |
| WO-1996011697-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1996-04-25 | — | — | WO | claimed |
| EP-0699074-A1 | THROMBIN INHIBITORS | MERCK & CO. INC. (US) | 1996-03-06 | — | — | EP | claimed |
| WO-1994025051-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1994-11-10 | — | — | WO | claimed |
| US-20250325469-A1 | Inhibitors of atp synthase - cosmetic and therapeutic uses | FORREST MICHAEL DAVID (GB) | 2025-10-23 | — | — | US | disclosed |
| EP-0460679-A2 | Endothelin antagonistic peptide derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0436189-A1 | Endothelin atagonistic cyclic pentapeptides | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250325469-A1 | Inhibitors of atp synthase - cosmetic and therapeutic uses | ATP5F1A, ATP5F1B, ATP5ME | CYP2A6 3981/4885DPP4 3288/4885DPP8 2655/4885 |
| US-20150274781-A1 | POTENT LIGANDS OF THE GHRELIN RECEPTOR | GIPR, GPR119, GRPR | CYP2A6 3651/4885DPP4 600/4885DPP8 574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.