Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937081 | 0.89 | HSP90AA1 (0.33) | ADORA2ACYP2C19 | |
| SCHEMBL4264484 | 0.86 | CYP1A2 (0.34) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL2906360 | 0.86 | SLC29A1 (0.36) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL2908881 | 0.80 | CYP1A2 (0.40) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL6053569 | 0.80 | CYP1A2 (0.40) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL2936424 | 0.80 | HK1 (0.34) | CYP1A2SLC29A1ADORA2ACYP2C19 | |
| SCHEMBL2913683 | 0.79 | SLC29A1 (0.37) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL2908647 | 0.78 | ABCB11 (0.39) | CYP1A2SLC29A1LMNARAB9ACYP3A4 | |
| SCHEMBL2943049 | 0.78 | CYP2C19 (0.34) | CYP1A2SLC29A1ADORA2ACYP2C19 | |
| SCHEMBL4271729 | 0.78 | CYP1A2 (0.35) | CYP1A2SLC29A1LMNARAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |