SCHEMBL29374271

SCHEMBL29374271

c1ccc2c3c(ncc2c1)CCCC3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 8/20 0.46
BCHE P06276 6/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
HSD17B10 Q99714 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CACNB4 O00305 1/20 0.46
CACNA1A O00555 1/20 0.46
SLC22A2 O15244 1/20 0.46
SLC22A1 O15245 1/20 0.46
ABCC4 O15439 1/20 0.46
CACNA1G O43497 1/20 0.46
CACNG3 O60359 1/20 0.46
CACNA1F O60840 1/20 0.46
CACNA1H O95180 1/20 0.46
APP P05067 1/20 0.46
FABP1 P07148 1/20 0.46
CHRM2 P08172 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921118 1.00 ACHE (0.46) ACHEBCHEALDH1A1TSHRHSD17B10
SCHEMBL8088682 0.96 ACHE (0.46) ACHEBCHEALDH1A1TSHRHSD17B10
Perchlorate SCHEMBL3915050 0.90 ACHE (0.40) ACHEBCHEALDH1A1TSHRHSD17B10
SCHEMBL18576434 0.88 KDM4E (0.47) ACHEBCHEALDH1A1TSHRHSD17B10
SCHEMBL726973 0.75 KDM4E (0.39) KDM4EGPR3TDP1
SCHEMBL637592 0.73 KDM4E (0.40) ACHEBCHEALDH1A1TSHRHSD17B10
SCHEMBL7901264 0.72 KDM4E (0.39) ACHEBCHEALDH1A1TSHRHSD17B10
SCHEMBL10379077 0.72 UHRF1 (0.40) BCHEALDH1A1HSD17B10KDM4ECYP1A2
SCHEMBL22235250 0.72 HSD17B10 (0.42) ACHEBCHEALDH1A1HSD17B10KDM4E
SCHEMBL15647796 0.72 ATM (0.40) ACHEBCHEALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022025242-A1 NOVEL STIRIPENTOL DERIVATIVE AND USE THEREOF 国立大学法人 岡山大学 2022-02-03 WO disclosed