Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 7/20 | 0.38 |
| ▸ | BCHE | P06276 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | FABP1 | P07148 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900644 | 0.97 | KDM4E (0.39) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL7893958 | 0.93 | KDM4E (0.41) | KDM4EGPR3ACHEALDH1A1HSD17B10 | |
| SCHEMBL7901266 | 0.78 | KIF11 (0.42) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL16535869 | 0.76 | KDM4E (0.48) | KDM4EGPR3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11743927 | 0.75 | KIF11 (0.43) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL17409892 | 0.74 | KIF11 (0.42) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL7900647 | 0.74 | KDM4E (0.41) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL22049815 | 0.73 | KDM4E (0.45) | KDM4EGPR3ALDH1A1TSHRHSD17B10 | |
| SCHEMBL29374271 | 0.72 | ACHE (0.46) | KDM4EGPR3ACHEBCHEALDH1A1 | |
| SCHEMBL2921118 | 0.72 | ACHE (0.46) | KDM4EGPR3ACHEBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187783-B1 | ANTITUMOR AGENTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-02-13 | — | — | US | disclosed |