SCHEMBL29374397

SCHEMBL29374397

O=C(O)C=Cc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.77
MAPT P10636 4/20 0.77
KMT2A Q03164 4/20 0.77
HPGD P15428 4/20 0.77
NPC1 O15118 4/20 0.77
RAB9A P51151 4/20 0.77
ALDH1A1 P00352 3/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
NFKB1 P19838 2/20 0.77
NFKB2 Q00653 1/20 0.77
RELA Q04206 1/20 0.77
KDM4E B2RXH2 3/20 0.64
LMNA P02545 2/20 0.64
TP53 P04637 1/20 0.64
MAPK1 P28482 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2D6 P10635 1/20 0.64
CYP2C9 P11712 1/20 0.64
PKM P14618 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357475 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL179873 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL29453353 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL15486687 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL15486685 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL531504 1.00 MEN1 (0.77) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL11103740 0.88 MEN1 (0.61) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL30090660 0.87 MAPT (1.00) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL656596 0.87 MAPT (1.00) MEN1MAPTKMT2AHPGDNPC1
SCHEMBL30734355 0.87 MAPT (1.00) MEN1MAPTKMT2AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040334-A Deuterium-labeled 3-indoleacrylic acid isotope compound and preparation method thereof 北京曼哈格生物科技有限公司 2025-05-27 CN claimed
US-20240096612-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND SHIMADZU CORPORATION (JP) 2024-03-21 US claimed
EP-4293350-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND Shimadzu Corporation (JP) 2023-12-20 EP claimed
CN-116854865-B Self-repairing scratch-resistant paint protective film and preparation method thereof 潍坊恒彩数码影像材料有限公司 2023-11-07 CN claimed
CN-116854865-A Self-repairing scratch-resistant paint protective film and preparation method thereof 潍坊恒彩数码影像材料有限公司 2023-10-10 CN claimed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN claimed
EP-3947702-A1 METHOD OF PRODUCING BACTERIALLY DERIVED INDOLE-3 -PROPIONIC ACID AND COMPOSITIONS COMPRISING SAME The Procter & Gamble Company (US) 2022-02-09 EP claimed
CN-122031539-A Pine bark polyphenol extract and preparation method and application thereof 北京农学院 2026-05-15 CN disclosed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP disclosed
US-20260115234-A1 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR BIOME APS (DK) 2026-04-30 US disclosed
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE MICROBA IP PTY LTD (AU) 2026-01-29 US disclosed
CN-120195409-A Composition for diagnosing sepsis and medicament for sepsis preventive treatment 北京大学第三医院(北京大学第三临床医学院) 2025-06-24 CN disclosed
US-20250186470-A1 Compositions and Methods Using Lactulose for Treating Disease THE UNIVERSITY OF CHICAGO (US) 2025-06-12 US disclosed
CN-113881597-B Lactobacillus reuteri capable of improving indole acrylic acid to regulate specific IgE 江南大学 2023-04-28 CN disclosed
CN-116003710-A Polyacrylic polymer modified substrate, preparation method thereof and application thereof in preparation of biochip 中国海洋大学 2023-04-25 CN disclosed
WO-2022241163-A1 METHODS OF USE OF OLIGOSACCHARIDE COMPOSITIONS FOR MODULATING MICROBIOTA AND THEIR METABOLIC PRODUCTS, AND AS THERAPEUTICS FOR HEALTH APPLICATIONS BCD BIOSCIENCE, INC. (US) 2022-11-17 WO disclosed
EP-4064862-A1 DESIGNED BACTERIAL COMPOSITIONS AND USES THEREOF Seres Therapeutics, Inc. (US) 2022-10-05 EP disclosed
WO-2022172500-A1 METHOD FOR MASS SPECTROMETRY OF ORGANIC SYNTHETIC COMPOUND 株式会社 島津製作所 2022-08-18 WO disclosed
EP-3947635-A1 COMPOSITION TO SUPPORT HEALTHY BRAIN FUNCTION The Procter & Gamble Company (US) 2022-02-09 EP disclosed
EP-3947702-A1 METHOD OF PRODUCING BACTERIALLY DERIVED INDOLE-3 -PROPIONIC ACID AND COMPOSITIONS COMPRISING SAME The Procter & Gamble Company (US) 2022-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115234-A1 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA AADAT, NAT1, IDO1 MEN1 3314/4885MAPT 3855/4885KMT2A 1796/4885
US-20260027161-A1 BACTERIAL STRAINS FOR TREATING DISEASE VIP, SI, ALPI MEN1 1746/4885MAPT 3556/4885KMT2A 4869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.