Nitrobenzylmercaptopurine Ribonucleoside

Nitrobenzylmercaptopurine Ribonucleoside

SCHEMBL29374837

O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 13/20 1.00
▸ CYP3A4 P08684 2/20 1.00
▸ TP53 P04637 1/20 1.00
▸ HIF1A Q16665 1/20 1.00
▸ ABCC4 O15439 1/20 1.00
▸ SLC28A3 Q9HAS3 1/20 1.00
▸ BLM P54132 1/20 1.00
▸ LMNA P02545 1/20 0.77
▸ RAB9A P51151 1/20 0.77
▸ PKM P14618 1/20 0.77
▸ HPGD P15428 1/20 0.77
▸ SMN1; SMN2 Q16637 1/20 0.77
▸ STAT6 P42226 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL290702 1.00 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL7617534 1.00 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL1321676 1.00 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
SCHEMBL1763081 0.87 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
SCHEMBL20579724 0.87 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
SCHEMBL1322160 0.87 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
SCHEMBL29784689 0.87 SLC29A1 (1.00) SLC29A1CYP3A4TP53HIF1AABCC4
6-Benzylthioinosine SCHEMBL3676029 0.86 SLC29A1 (1.00) SLC29A1STAT6
6-Benzylthioinosine SCHEMBL7617372 0.86 SLC29A1 (1.00) SLC29A1STAT6
6-Benzylthioinosine SCHEMBL7617380 0.86 SLC29A1 (1.00) SLC29A1STAT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3737953-B1 INTEGRATED CIRCUIT WORKLOAD, TEMPERATURE AND/OR SUB-THRESHOLD LEAKAGE SENSOR PROTEANTECS LTD (IL) 2026-03-04 — — EP claimed
EP-3411724-B1 AGEING DETECTOR FOR AN ELECTRICAL CIRCUIT COMPONENT, METHOD FOR MONITORING AGEING OF A CIRCUIT COMPONENT, COMPONENT AND CONTROL DEVICE BOSCH GMBH ROBERT (DE) 2025-12-17 — — EP claimed
CN-119986315-A High-precision analog circuit, chip and IP for monitoring NBTI effect 西安电子科技大学 2025-05-13 — — CN claimed
CN-119438851-B BTI test circuit, and BTI test method and device for MOS (metal oxide semiconductor) tube in wafer 安徽大学 2025-05-13 — — CN claimed
CN-119918476-A Analysis method and device for integrated circuit coupling failure 西安电子科技大学 2025-05-02 — — CN claimed
CN-119918475-A Integrated circuit coupling failure analysis method and device based on neural network 西安电子科技大学 2025-05-02 — — CN claimed
CN-119831070-A Federal learning incentive scheme based on Nash negotiation theory 四川大学 2025-04-15 — — CN claimed
CN-119716467-A Aging analysis method and related equipment 海光集成电路设计(北京)有限公司 2025-03-28 — — CN claimed
CN-119716437-A Measurement method and measurement system, and evaluation method and evaluation system for device reliability 青岛澳柯玛云联信息技术有限公司 2025-03-28 — — CN claimed
US-20250104792-A1 APPARATUS INCLUDING BTI CONTROLLER MICRON TECHNOLOGY, INC. (US) 2025-03-27 — — US claimed
CN-115391975-A NBTI effect recovery phase simulation method based on TCAD 西安电子科技大学 2022-11-25 — — CN claimed
CN-115312391-A Method for improving NBTI effect 上海华力集成电路制造有限公司 2022-11-08 — — CN claimed
CN-217693278-U Clock transmission circuit suitable for image sensor 四川创安微电子有限公司 2022-10-28 — — CN claimed
CN-114841097-A Circuit path grade NBTI (negative bias temperature instability) aging prediction method and device based on key gate 安徽理工大学 2022-08-02 — — CN claimed
WO-2022159582-A2 MULTIVALENT CHLOROTOXIN CHIMERIC ANTIGEN RECEPTORS IN8bio, Inc. (US) 2022-07-28 — — WO claimed
CN-216819967-U Repeater for improving negative bias temperature instability clock path and image sensor 四川创安微电子有限公司 2022-06-24 — — CN claimed
CN-114499488-A Circuit structure for relieving aging of integrated circuit and control method 西安电子科技大学 2022-05-13 — — CN claimed
CN-111381139-B Semiconductor device testing method and semiconductor device testing system 长鑫存储技术有限公司 2022-04-26 — — CN claimed
CN-108717484-B Method and system for alleviating NBTI effect by low-switching random input waveform 安徽理工大学 2022-04-19 — — CN claimed
CN-114019249-A NBTI test method and device under coupling of ionizing radiation 中国电子产品可靠性与环境试验研究所((工业和信息化部电子第五研究所)(中国赛宝实验室)) 2022-02-08 — — CN claimed
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