Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 13/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 1.00 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | STAT6 | P42226 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL290702 | 1.00 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL29374837 | 1.00 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| Nitrobenzylmercaptopurine Ribonucleoside SCHEMBL1321676 | 1.00 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| SCHEMBL1763081 | 0.87 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| SCHEMBL20579724 | 0.87 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| SCHEMBL1322160 | 0.87 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| SCHEMBL29784689 | 0.87 | SLC29A1 (1.00) | SLC29A1CYP3A4TP53HIF1AABCC4 | |
| 6-Benzylthioinosine SCHEMBL3676029 | 0.86 | SLC29A1 (1.00) | SLC29A1STAT6 | |
| 6-Benzylthioinosine SCHEMBL7617372 | 0.86 | SLC29A1 (1.00) | SLC29A1STAT6 | |
| 6-Benzylthioinosine SCHEMBL7617380 | 0.86 | SLC29A1 (1.00) | SLC29A1STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3060566-A1 | COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN | Academia Sinica (TW) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061426-A1 | COMPOUNDS FOR USE IN PREVENTION AND TREATMENT OF NEURODEGENERATIVE DISEASES AND PAIN | ACADEMIA SINICA (TW) | 2015-04-30 | — | — | WO | disclosed |
| EP-0755255-A4 | TREATMENT OF TOXOPLASMOSIS | RES CORP TECHNOLOGIES INC (US) | 2002-07-24 | — | — | EP | disclosed |
| US-5773424-A | PARASITICIDE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0755255-A1 | TREATMENT OF TOXOPLASMOSIS | UNIVERSITY OF ALABAMA, BIRMINGHAM RESEARCH FOUNDATION (US) | 1997-01-29 | — | — | EP | disclosed |
| WO-1996018398-A1 | TREATMENT OF TOXOPLASMOSIS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-06-20 | — | — | WO | disclosed |