SCHEMBL29375248

SCHEMBL29375248

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 9/20 0.57
OPRM1 P35372 8/20 0.57
BACE1 P56817 9/20 0.49
BACE2 Q9Y5Z0 1/20 0.49
OPRK1 P41145 3/20 0.49
CTSD P07339 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375819 0.94 OPRM1 (0.54) OPRD1OPRM1BACE1BACE2OPRK1
SCHEMBL30054207 0.93 BACE1 (0.51) OPRD1OPRM1BACE1BACE2CTSD
SCHEMBL29674783 0.90 OPRM1 (0.53) OPRD1OPRM1BACE1BACE2OPRK1
SCHEMBL18047563 0.89 BACE1 (0.56) OPRD1OPRM1BACE1BACE2CTSD
SCHEMBL29804647 0.89 BACE1 (0.51) OPRD1OPRM1BACE1BACE2OPRK1
SCHEMBL29375389 0.88 BACE1 (0.56) OPRD1OPRM1BACE1BACE2CTSD
SCHEMBL29375740 0.88 BACE1 (0.56) OPRD1OPRM1BACE1BACE2CTSD
SCHEMBL29436286 0.87 OPRM1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL31215075 0.87 OPRD1 (0.64) OPRD1OPRM1OPRK1
SCHEMBL31257069 0.85 OPRD1 (0.57) OPRD1OPRM1BACE1OPRK1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11518794-B2 Synthesis method for liraglutide with low racemate impurity Shenzhen JYMed Technology Co., Ltd. (CN) 2022-12-06 US claimed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP claimed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US claimed
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof ASTRAZENECA AB (SE) 2024-10-15 US disclosed
US-11518794-B2 Synthesis method for liraglutide with low racemate impurity Shenzhen JYMed Technology Co., Ltd. (CN) 2022-12-06 US disclosed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP OPRD1 3405/4885OPRM1 4009/4885BACE1 569/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP OPRD1 3405/4885OPRM1 4009/4885BACE1 569/4885
US-12115225-B2 GLP-1 receptor ligand moiety conjugated oligonucleotides and uses thereof GLP1R, GIPR, GRPR OPRD1 1624/4885OPRM1 695/4885BACE1 2130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.