Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3002216 | 1.00 | ALOX5 (0.55) | ALOX5SMN1; SMN2STAT3HTTMAOB | |
| SCHEMBL629848 | 0.89 | ALOX5 (0.65) | ALOX5SMN1; SMN2MAOBMAPTL3MBTL1 | |
| SCHEMBL629661 | 0.89 | ALOX5 (0.65) | ALOX5SMN1; SMN2MAOBMAPTL3MBTL1 | |
| SCHEMBL3133767 | 0.86 | LTA4H (0.55) | ALOX5SMN1; SMN2MAOBMAPTL3MBTL1 | |
| SCHEMBL30026191 | 0.86 | MAOB (0.50) | ALOX5SMN1; SMN2HTTMAOBMAPT | |
| SCHEMBL22412158 | 0.86 | MAOB (0.50) | ALOX5SMN1; SMN2HTTMAOBMAPT | |
| SCHEMBL22412255 | 0.86 | MAOB (0.50) | ALOX5SMN1; SMN2HTTMAOBMAPT | |
| SCHEMBL30461784 | 0.86 | MAOB (0.50) | ALOX5SMN1; SMN2HTTMAOBMAPT | |
| SCHEMBL23539106 | 0.85 | SMN1; SMN2 (0.46) | ALOX5SMN1; SMN2STAT3HTTMAOB | |
| SCHEMBL30559872 | 0.85 | SMN1; SMN2 (0.46) | ALOX5SMN1; SMN2STAT3HTTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348455-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332873-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114025844-B | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-114025844-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2022-02-08 | — | — | CN | disclosed |