Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.49 |
| ▸ | NPY1R | P25929 | 8/20 | 0.49 |
| ▸ | NPY2R | P49146 | 6/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29674974 | 0.97 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5R | |
| Trifluoroacetic Acid SCHEMBL29374860 | 0.91 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RITGB1 | |
| SCHEMBL31045724 | 0.90 | CA12 (0.44) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL29790963 | 0.90 | CA12 (0.44) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL30619377 | 0.88 | KDM4E (0.45) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL31045822 | 0.88 | KDM4E (0.45) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL29614667 | 0.87 | NPY4R (0.46) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL8499114 | 0.87 | KDM4E (0.48) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL7204719 | 0.87 | KDM4E (0.48) | NPY4RNPY1RNPY2RNPY5RKDM4E | |
| SCHEMBL7204729 | 0.87 | KDM4E (0.48) | NPY4RNPY1RNPY2RNPY5RKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946332-A1 | PROTEASE-ACTIVATED RECEPTOR-2 INHIBITORS FOR THE TREATMENT OF SENSORY NEUROPATHY INDUCED BY A MARINE NEUROTOXIC POISONING | Université de Bretagne Occidentale (FR) | 2022-02-09 | — | — | EP | disclosed |