Phthalimide

Phthalimide

SCHEMBL29375323

O=C1NC(=O)c2ccccc21.[K]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 1/20 0.94
▸ CASP7 P55210 3/20 0.75
▸ CASP3 P42574 2/20 0.75
▸ CASP6 P55212 2/20 0.75
▸ CASP8 Q14790 2/20 0.75
▸ CASP2 P42575 1/20 0.75
▸ PARP1 P09874 4/20 0.56
▸ PDGFRA P16234 1/20 0.56
▸ FER P16591 1/20 0.56
▸ LTK P29376 1/20 0.56
▸ CDK8 P49336 1/20 0.56
▸ ACVR1 Q04771 1/20 0.56
▸ LRRK2 Q5S007 1/20 0.56
▸ DYRK1B Q9Y463 1/20 0.56
▸ MAPK1 P28482 4/20 0.52
▸ LMNA P02545 3/20 0.52
▸ SMN1; SMN2 Q16637 3/20 0.52
▸ HSD17B10 Q99714 1/20 0.52
▸ MAOA P21397 5/20 0.50
▸ MAOB P27338 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL9231 1.00 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL1205294 1.00 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10592859 0.97 GSK3B (0.88) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7771670 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL11040503 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL29366030 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL30125197 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL64 0.97 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL4297661 0.94 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121758308-B Preparation method of L-2, 4-diaminobutyric acid dihydrochloride 山东省农药科学研究院 2026-05-19 — — CN claimed
EP-3560932-B1 PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AND SYNTHETIC INTERMEDIATES OF SAME JAPAN TOBACCO INC (JP) 2026-03-11 — — EP claimed
EP-4430102-B1 POLYOXAZOLINE BASED THERMAL LATENT CURING AGENTS FOR THERMOSET RESINS UNIV SABANCI (TR) 2025-06-25 — — EP claimed
CN-116217172-B Synthetic method of composite fiber reinforced cement-based material based on hybrid effect 北京中震建筑科学研究院有限公司 2025-04-29 — — CN claimed
CN-119798290-A Synthesis method of bortezomib intermediate 江苏希迪制药有限公司 2025-04-11 — — CN claimed
CN-119735730-A Acoustic matching material, preparation method thereof, ultrasonic transducer, ultrasonic probe and ultrasonic imaging device 武汉联影医疗科技有限公司 2025-04-01 — — CN claimed
CN-119591579-A Photosensitive mass spectrometry probe, preparation method thereof and application thereof in mass spectrometry detection 武汉纺织大学 2025-03-11 — — CN claimed
CN-119219642-A Quinolizine organic electrode material with multiple active sites, and preparation method and application thereof 常州大学 2024-12-31 — — CN claimed
CN-114276266-B Preparation method of 4-amino-2-fluorobenzamide 兰州康鹏威耳化工有限公司 2024-10-11 — — CN claimed
CN-117756720-B Polymerizable quaternary ammonium salt antibacterial agent, preparation thereof and application thereof in synthesis of antibacterial polyester 东方电气股份有限公司 2024-09-13 — — CN claimed
CN-114539458-A Porous resin applied to solid phase synthesis and preparation method thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 — — CN claimed
CN-114540889-A Copper plating additive, copper plating solution and application thereof 江阴纳力新材料科技有限公司 2022-05-27 — — CN claimed
CN-114539459-A Solid-phase synthesis carrier and preparation method and application thereof 西安蓝晓科技新材料股份有限公司 2022-05-27 — — CN claimed
EP-3318591-B1 HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, INTERMEDIATE FOR PRODUCTION OF HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL, METHODS FOR PRODUCING SAME, AND HETERO TYPE MONODISPERSED POLYETHYLENE GLYCOL CONJUGATE TOHOKU TECHNO ARCH CO LTD (JP) 2022-05-18 — — EP claimed
CN-114436848-A Synthesis method of 5(6) -amino-1- (4-aminophenyl) -1,3,3-trimethylindane 山东华夏神舟新材料有限公司 2022-05-06 — — CN claimed
CN-112341373-B Preparation method of ftibamzone 山东嘉成医药科技有限公司 2022-04-08 — — CN claimed
CN-114276266-A Preparation method of 4-amino-2-fluorobenzamide 兰州康鹏威耳化工有限公司 2022-04-05 — — CN claimed
CN-112759542-B Drug intermediate, preparation and application thereof 上海现代制药股份有限公司 2022-04-01 — — CN claimed
CN-109096171-B Method for preparing deuterated diphenylurea 苏州泽璟生物制药股份有限公司 2022-04-01 — — CN claimed
CN-114230490-A Preparation method of N-alkylated diamine 乐威医药(江苏)股份有限公司 2022-03-25 — — CN claimed
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