Ronnel

Ronnel

SCHEMBL29375404

COP(=S)(OC)Oc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
LMNA P02545 3/20 0.38
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 6/20 0.35
CYP3A4 P08684 4/20 0.35
HSD17B10 Q99714 3/20 0.35
TSHR P16473 3/20 0.35
MAPK1 P28482 2/20 0.34
MAPT P10636 2/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TP53 P04637 1/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MPO P05164 1/20 0.33
TPO P07202 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ronnel SCHEMBL6736758 1.00 TDP1 (0.53) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL19438 1.00 TDP1 (0.53) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL3272218 1.00 TDP1 (0.53) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL11879973 1.00 TDP1 (0.53) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL713515 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL9178207 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL8143453 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL11798525 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL8927417 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1
Ronnel SCHEMBL6832096 0.98 TDP1 (0.51) TDP1MEN1KMT2ALMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115460922-B Powder formulations comprising a carrier to which the active ingredient is applied by a solvent 发现号收购集团 2025-05-09 CN disclosed
CN-119817574-A Powder formulations comprising a carrier to which the active ingredient is applied by a solvent 发现号收购集团 2025-04-15 CN disclosed
WO-2024227082-A1 BASE-EDITING PERTURBATION SCREENS AND USES THEREOF SANKARAN VIJAY (US) 2024-10-31 WO disclosed
CN-118745174-A Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达参股股份有限公司 2024-10-08 CN disclosed
US-12102653-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2024-10-01 US disclosed
CN-111836810-B Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达参股股份有限公司 2024-06-25 CN disclosed
CN-117715520-A Compositions and methods for improving the rain tolerance of proteins on plant surfaces 诺维信公司 2024-03-15 CN disclosed
US-20240000841-A1 LIGAND REGULATED PROTEIN-PROTEIN INTERACTION SYSTEM ST ANNA KINDERKREBSFORSCHUNG (AT) 2024-01-04 US disclosed
US-11844813-B2 Ligand regulated protein-protein interaction system ST. ANNA KINDERKREBSFORSCHUNG (AT) 2023-12-19 US disclosed
WO-2023191208-A1 ROOM TEMPERATURE EMULSIFIED ASPHALT MIXTURE, AND METHOD FOR MANUFACTURING SAME 에이원유화(주) 2023-10-05 WO disclosed
CN-112376297-B Waterproof agent, dyeing agent and environment-friendly dyeing process for chrome-free tanned sheep-cut napped leather 焦作隆丰皮草企业有限公司 2023-08-01 CN disclosed
WO-2023055165-A1 RAPID-SETTING NON-ADHESIVE RUBBER-BASED MODIFIED EMULSIFIED ASPHALT COMPOSITION COMPRISING HIGH-FUNCTIONAL LATEX, AND METHOD FOR MANUFACTURING SAME 에이원유화(주) 2023-04-06 WO disclosed
CN-111194314-B Microbicidal pyridine amide derivative 先正达参股股份有限公司 2022-12-30 CN disclosed
CN-115348819-A Non-corrosive formulated compositions for nitrogen inhibitors 沃戴申生命科学美国有限责任公司 2022-11-15 CN disclosed
CN-114451413-A Use of acyclic picolinamides as fungicides for controlling phytopathogenic fungi in vegetables 美国陶氏益农公司 2022-05-10 CN disclosed
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) ST. ANNA KINDERKREBSFORSCHUNG (AT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041687-A1 A GROUP OF CHIMERIC ANTIGEN RECEPTORS (CARS) CARS1, CD74, HAVCR2 TDP1 4703/4885MEN1 4288/4885KMT2A 2971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.