Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 2/20 | 0.38 |
| ▸ | CIT | O14578 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502463 | 1.00 | IKBKB (0.38) | IKBKBCHUKCITEGFRCSNK1D | |
| SCHEMBL15828666 | 0.82 | IKBKB (0.38) | IKBKBCHUKKIT | |
| SCHEMBL22524176 | 0.80 | RET (0.40) | IKBKBCHUKCITEGFRCSNK1D | |
| SCHEMBL30248822 | 0.80 | RET (0.40) | IKBKBCHUKCITEGFRCSNK1D | |
| SCHEMBL17538627 | 0.79 | CSNK1D (0.38) | IKBKBCHUKCITEGFRCSNK1D | |
| SCHEMBL22524383 | 0.75 | IKBKB (0.33) | IKBKBCHUKCITCSNK1DMAPK14 | |
| SCHEMBL22490018 | 0.75 | CIT (0.38) | IKBKBCHUKCITEGFRCSNK1D | |
| SCHEMBL9048053 | 0.73 | ABL1 (0.35) | EGFRKIT | |
| SCHEMBL3647958 | 0.72 | TRPA1 (0.44) | KIT | |
| SCHEMBL22524214 | 0.68 | SMN1; SMN2 (0.43) | TP53HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947390-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | Mitokinin, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114026093-A | Compositions for treating neurodegenerative and mitochondrial diseases and methods of use thereof | 麦托吉宁公司 | 2022-02-08 | — | — | CN | disclosed |