Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083893 | 1.00 | GLS (0.50) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL30448181 | 0.90 | GLS (0.46) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL31304459 | 0.87 | GLS (0.53) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL14910335 | 0.87 | GLS (0.53) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL15910780 | 0.85 | GLS (0.51) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL3354657 | 0.83 | GLS (0.49) | GLSSLC6A2MAPTPOLBNOS1 | |
| SCHEMBL3355202 | 0.81 | GLS (0.50) | GLSMAPTPOLBALDH1A1NPC1 | |
| SCHEMBL29377201 | 0.81 | GLS (0.50) | GLSMAPTPOLBALDH1A1NPC1 | |
| SCHEMBL3357246 | 0.79 | MAPT (0.51) | GLSMAPTPOLBALDH1A1CYP1A2 | |
| SCHEMBL3355498 | 0.78 | GLS (0.47) | GLSMAPTPOLBALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322683-A | Compounds as C5AR inhibitors | 科越医药(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022028586-A1 | COMPOUNDS AS C5AR INHIBITORS | KIRA PHARMACEUTICALS (SUZHOU) LTD. (CN) | 2022-02-10 | — | — | WO | disclosed |