Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304459 | 0.92 | GLS (0.53) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL14910335 | 0.92 | GLS (0.53) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL3357749 | 0.91 | ALDH1A1 (0.43) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL15910780 | 0.89 | GLS (0.51) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL13537593 | 0.87 | MEN1 (0.38) | GLSALDH1A1MAPTMEN1PKM | |
| SCHEMBL3355202 | 0.85 | GLS (0.50) | GLSALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL29377201 | 0.85 | GLS (0.50) | GLSALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL27083893 | 0.83 | GLS (0.50) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL29375545 | 0.83 | GLS (0.50) | GLSALDH1A1HTR3EHTR3BCYP1A2 | |
| SCHEMBL3357246 | 0.83 | MAPT (0.51) | GLSALDH1A1CYP1A2SIRT2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |