Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22466074 | 1.00 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL30903838 | 0.96 | RAB9A (0.49) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL22465913 | 0.88 | MEN1 (0.45) | MRGPRX4PTGER1NR4A2 | |
| SCHEMBL29375274 | 0.88 | MEN1 (0.45) | MRGPRX4PTGER1NR4A2 | |
| SCHEMBL30903834 | 0.84 | MEN1 (0.47) | RAB9ASMN1; SMN2NPC1MRGPRX4PTGER1 | |
| SCHEMBL22466085 | 0.83 | SENP5 (0.46) | RAB9ASMN1; SMN2NPC1TP53RXFP1 | |
| SCHEMBL29378052 | 0.83 | SENP5 (0.46) | RAB9ASMN1; SMN2NPC1TP53RXFP1 | |
| SCHEMBL22468980 | 0.83 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1POLBPLA2G4B | |
| SCHEMBL22465887 | 0.83 | MAOB (0.37) | RAB9ANPC1 | |
| SCHEMBL22466141 | 0.83 | MAOB (0.37) | ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3946599-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |