SCHEMBL242563

SCHEMBL242563

COc1cc(C(=O)O)ccc1OCc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 4/20 0.77
NPC1 O15118 3/20 0.77
RAB9A P51151 3/20 0.77
SMN1; SMN2 Q16637 2/20 0.77
HPGD P15428 1/20 0.77
RXRA P19793 1/20 0.73
TSHR P16473 1/20 0.68
SMPD1 P17405 1/20 0.67
HDAC1 Q13547 1/20 0.67
HDAC8 Q9BY41 1/20 0.67
HDAC6 Q9UBN7 1/20 0.67
KDM4E B2RXH2 1/20 0.65
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
CA12 O43570 1/20 0.65
CA1 P00915 1/20 0.65
CA2 P00918 1/20 0.65
CA4 P22748 1/20 0.65
CA6 P23280 1/20 0.65
CA7 P43166 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11277266 0.98 MRGPRX4 (0.75) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL29375753 0.94 SMPD1 (0.75) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL1029034 0.94 SMPD1 (0.75) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL11271923 0.93 SMPD1 (0.73) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
Hydrochloric Acid SCHEMBL6586504 0.93 SMPD1 (0.73) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL27881765 0.91 NPC1 (0.77) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL1600077 0.91 MRGPRX4 (0.62) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL29556736 0.91 MRGPRX4 (0.62) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL31025721 0.90 NPC1 (0.75) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL340620 0.90 NPC1 (0.75) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US disclosed
EP-4678637-A1 NOVEL FLAVONE DERIVATIVE AND USE THEREOF IN ALLEVIATING PULMONARY FIBROSIS A-chembio Co., Ltd (KR) 2026-01-14 EP disclosed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 US disclosed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US disclosed
US-12478695-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-11-25 US disclosed
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-11-18 US disclosed
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-10-07 US disclosed
EP-3580302-B1 REDOX FLOW BATTERY ELECTROLYTES CMBLU ENERGY AG (DE) 2025-09-17 EP disclosed
EP-3580389-B1 NOVEL METHODS FOR PROCESSING LIGNOCELLULOSIC MATERIAL CMBLU ENERGY AG (DE) 2025-09-17 EP disclosed
EP-0635480-B1 Anthracene derivatives WAKO PURE CHEM IND LTD (JP) 1997-03-19 EP disclosed
US-5576359-A ANTHRACENE DERIVATIVE, SOLVENT, COMPOUND CONTAINING GLYCIDYL GROUPS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-19 US disclosed
EP-0636941-B1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEM IND LTD (JP) 1996-03-20 EP disclosed
US-5498748-A PHENOLIC CROSSLINKER FOR A POLYGLYCIDYL METHACRYLATE TO FORM A MATERIAL USED AS AN ANTIREFLECTION COATING FOR DEEP UV LIGHT SUCH AS KRF EXIMER LASERS IN SEMICONDUCTOR PHOTORESISTS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-03-12 US disclosed
EP-0636941-A1 Deep ultraviolet absorbent and its use in pattern formation WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-02-01 EP disclosed
EP-0635480-A1 Anthracene derivatives WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1995-01-25 EP disclosed
EP-0613879-A1 PHELLODENDRINE ANALOGS AND ALLERGY TYPE IV SUPPRESSOR CONTAINING THE SAME AS ACTIVE INGREDIENT TSUMURA & CO. (JP) 1994-09-07 EP disclosed
EP-0019081-B1 FLAVONE DERIVATIVES, THEIR PREPARATION, THESE NOVEL AND KNOWN FLAVONES AS ANTIVIRAL AGENTS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-10-24 EP disclosed
EP-0019081-A1 Flavone derivatives, their preparation, these novel and known flavones as antiviral agents, and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-11-26 EP disclosed
US-4098816-A HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS BEECHAM GROUP LIMITED (GB) 1978-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD4, CD2, B2M MRGPRX4 2210/4885NPC1 4204/4885RAB9A 4485/4885
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM MRGPRX4 3518/4885NPC1 3147/4885RAB9A 3843/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM MRGPRX4 3518/4885NPC1 3147/4885RAB9A 3843/4885
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM MRGPRX4 3518/4885NPC1 3147/4885RAB9A 3843/4885
US-12478695-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof SLC25A1, GCDH, FH MRGPRX4 4104/4885NPC1 4195/4885RAB9A 4030/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 MRGPRX4 1535/4885NPC1 1370/4885RAB9A 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.