Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ITK | Q08881 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187575 | 1.00 | KDR (0.58) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL31591007 | 1.00 | KDR (0.58) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL10176240 | 0.96 | KDR (0.61) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL11363931 | 0.90 | KDR (0.63) | KDRCHEK1KDM4ERAB9AMAPT | |
| Acetic Acid SCHEMBL29113892 | 0.89 | KDR (0.51) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL5051826 | 0.86 | KDR (0.68) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL13814199 | 0.84 | RAB9A (0.56) | KDRCHEK1KDM4ERAB9AMAPT | |
| SCHEMBL31655505 | 0.84 | KDR (0.53) | KDRCHEK1KDM4ERAB9AMAPT | |
| Methane SCHEMBL28704887 | 0.84 | KDR (0.66) | KDRCHEK1KDM4ERAB9AMAPT | |
| Benzene SCHEMBL27629233 | 0.84 | RAB9A (0.69) | KDRCHEK1KDM4ERAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102562-B | Naphtho [2,1-b ] indolo [2,3-d ] cyclooctalactone derivative and preparation method thereof | 江苏师范大学 | 2024-11-26 | — | — | CN | claimed |
| CN-116102562-A | Naphtho [2,1-b ] indolo [2,3-d ] cyclooctalactone derivative and preparation method thereof | 江苏师范大学 | 2023-05-12 | — | — | CN | claimed |
| US-12503481-B2 | Three-dimensional organic sandwich chirality and its synthetic assembly | TEXAS TECH UNIVERSITY SYSTEM (US) | 2025-12-23 | — | — | US | disclosed |
| CN-119367815-A | Device for solid phase extraction and method of use thereof | 水技术公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-116102562-B | Naphtho [2,1-b ] indolo [2,3-d ] cyclooctalactone derivative and preparation method thereof | 江苏师范大学 | 2024-11-26 | — | — | CN | disclosed |
| CN-117447376-A | Siama-1 receptor inhibitors of the bicyclic structure | 苏州恩华生物医药科技有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-114702428-B | Siama-1 receptor inhibitors of the bicyclic structure | 苏州恩华生物医药科技有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-116102562-A | Naphtho [2,1-b ] indolo [2,3-d ] cyclooctalactone derivative and preparation method thereof | 江苏师范大学 | 2023-05-12 | — | — | CN | disclosed |
| CN-114702428-A | Linbicyclic structure sigma-1 receptor inhibitors | 苏州恩华生物医药科技有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-113024435-B | Linbicyclic structure sigma-1 receptor inhibitors | 苏州恩华生物医药科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| US-20220041634-A1 | Three-Dimensional Organic Sandwich Chirality and Its Synthetic Assembly | TEXAS TECH UNIVERSITY SYSTEM | 2022-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041634-A1 | Three-Dimensional Organic Sandwich Chirality and Its Synthetic Assembly | WNT3, CTNNB1, ORC3 | KDR 3967/4885CHEK1 897/4885KDM4E 1450/4885 |
| US-12503481-B2 | Three-dimensional organic sandwich chirality and its synthetic assembly | WNT3, CTNNB1, ORC3 | KDR 3967/4885CHEK1 897/4885KDM4E 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.