SCHEMBL29375916

SCHEMBL29375916

Cc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDPK1 O15530 1/20 0.66
▸ GDA Q9Y2T3 1/20 0.66
▸ PI4KA P42356 2/20 0.52
▸ PI4K2B Q8TCG2 2/20 0.52
▸ PI4K2A Q9BTU6 2/20 0.52
▸ PI4KB Q9UBF8 2/20 0.52
▸ LMNA P02545 1/20 0.52
▸ DRD3 P35462 1/20 0.52
▸ XDH P47989 1/20 0.52
▸ LRRK2 Q5S007 1/20 0.52
▸ MAP3K5 Q99683 1/20 0.47
▸ CDK2 P24941 5/20 0.47
▸ DPP4 P27487 1/20 0.47
▸ PNP P00491 1/20 0.46
▸ CDK1 P06493 4/20 0.44
▸ CCNB1 P14635 4/20 0.44
▸ CCNA2 P20248 4/20 0.44
▸ CCNA1 P78396 4/20 0.44
▸ POLA1 P09884 2/20 0.43
▸ PIN1 Q13526 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19780 1.00 PDPK1 (0.66) PDPK1GDAPI4KAPI4K2BPI4K2A
Sulfuric Acid SCHEMBL30128586 0.90 PDPK1 (0.54) PDPK1GDAPI4KAPI4K2BPI4K2A
Furan SCHEMBL28428662 0.88 PDPK1 (0.53) PDPK1GDAPI4KAPI4K2BPI4K2A
Thioguanine SCHEMBL9153902 0.86 PDPK1 (0.63) PDPK1GDAPI4KAPI4K2BPI4K2A
Triphosphate SCHEMBL30196670 0.82 PDPK1 (0.46) PDPK1GDAPI4KAPI4K2BPI4K2A
2,6-Diaminopurine SCHEMBL29143272 0.80 PDPK1 (0.92) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL542009 0.79 PDPK1 (0.59) PDPK1GDAPI4KAPI4K2BPI4K2A
2,6-Diaminopurine SCHEMBL24053 0.79 PDPK1 (1.00) PDPK1GDAPI4KAPI4K2BPI4K2A
SCHEMBL20611894 0.79 PDPK1 (0.44) PDPK1GDAXDHLRRK2MAP3K5
SCHEMBL29366073 0.79 PDPK1 (0.44) PDPK1GDAXDHLRRK2MAP3K5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028668-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-01-29 — — US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 — — EP claimed
EP-4565717-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES Ramot at Tel-Aviv University Ltd. (IL) 2025-06-11 — — EP claimed
EP-4565692-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-06-11 — — EP claimed
CN-120041540-A Novel method for efficiently cutting solid-phase surface DNA chain and application thereof in sequencing 深圳赛陆医疗科技有限公司 2025-05-27 — — CN claimed
CN-119876360-A Linearization method for NGS sequencing, sequencing chip and sequencing method 深圳赛陆医疗科技有限公司 2025-04-25 — — CN claimed
US-20250129308-A1 SEMICONDUCTOR TREATMENT LIQUID, TREATMENT METHOD FOR OBJECT TO BE TREATED, AND MANUFACTURING METHOD OF ELECTRONIC DEVICE FUJIFILM CORP (JP) 2025-04-24 — — US claimed
WO-2025060642-A1 MODIFIED NUCLEOTIDE COMPOUND, OLIGONUCLEOTIDE THEREOF, AND USE THEREOF 广州必贝特医药股份有限公司 2025-03-27 — — WO claimed
CN-119685462-A Linearization method for NGS sequencing, sequencing chip and sequencing method 深圳赛陆医疗科技有限公司 2025-03-25 — — CN claimed
CN-118914565-A N6Methyladenine (m)6A) Application of reading protein hnRNPA2B1 in diagnosis and treatment of disuse osteoporosis 中国人民解放军空军军医大学 2024-11-08 — — CN claimed
CN-116790733-A Deaminase-assisted N in RNA 6 Method for the localization analysis of methyladenine 武汉大学 2023-09-22 — — CN claimed
CN-116763938-A Extracellular vesicle nucleic acid nano-drug delivery system, preparation method and application thereof 国家纳米科学中心 2023-09-19 — — CN claimed
US-20230212644-A1 IMAGING AND SEQUENCING PROTEIN-DNA INTERACTIONS IN SINGLE CELLS USING INTEGRATED MICROFLUIDICS CZ BIOHUB SF, LLC 2023-07-06 — — US claimed
CN-115852494-A Construction method of target sequencing library 清华大学 2023-03-28 — — CN claimed
CN-115786453-A Analysis method and kit for single base resolution positioning of N6-methyladenine in DNA assisted by deaminase 深圳市小分子新药创新中心有限公司 2023-03-14 — — CN claimed
CN-115404350-A Method for recovering gold by using nitrogen-containing basic group compound modified adsorption resin 华中科技大学 2022-11-29 — — CN claimed
EP-4058152-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER The Board of Regents of the University of Oklahoma (US) 2022-09-21 — — EP claimed
CN-114137053-B Antibody enzyme-free assisted photoelectrochemical sensor for detecting m 6 Method A 山东农业大学 2022-08-19 — — CN claimed
CN-114807328-A Method for marking and identifying single-base resolution DNA 浙江大学 2022-07-29 — — CN claimed
CN-114137053-A Antibody enzyme-free assisted photoelectrochemical sensor for detecting m6Method A 山东农业大学 2022-03-04 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028668-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES NCL, PCNA, DNMT1 PDPK1 3593/4885GDA 247/4885PI4KA 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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